angiogenesis is the creation of new blood vessels tumors use it to keep growing well our fatty tissue also needs a blood supply to expand so might an anti-angiogenic approach work for weight loss too I'll explore that in this video and the next [Music] many of our modern Frontline therapies against cancer incorporate anti-angiogenesis strategies from the Greek words angio meaning vessel and Genesis meaning creation so anti-angiogenesis is opposing the creation of blood vessels in other words fighting cancer by cutting off tumor supply lines some cancers are only able to grow to about the size of the
tip of a ballpoint pen without a blood supply tumor growth then stalls autopsy studies show that virtually everyone has these tiny tumors in them by age 70. cancer without disease can therefore be considered the normal State during aging to commandeer blood supply tumors diabolically release angiogenic factors chemicals that cause new blood vessels to sprout towards the cancer once a blood vessel reaches the tumor and attaches it's Off to the Races the tumor can then take off exponentially by starving cancer of its blood supply chemotherapy that blocks this process can sometimes cause tumors to shrink but
ideally we wouldn't have to wait until such a late stage to nip them in the bud that's where our diet can come in many of the phytonutrients we know and love in tea spices berries broccoli and beans have anti-angiogenic properties given the power of plants the foundation of an anti-angiogenic approach to cancer has been considered a whole food plant-based diet but the title of this video is targeting angiogenesis to lose weight what does this have to do with obesity well think about it tumors aren't the only tissue in the body with expanding volume the average
tumor picked up by mammograms is only about the size of a marble and it can take breast cancer decades to grow whereas over feed people and you can easily add an entire pound of fatty tissue in a matter of days and body fat is highly vascularized each fat cell in our body is essentially surrounded by tiny blood vessels enlarged liposuction operations a third of what's vacuumed out is straight blood throughout adulthood our fatty tissue is constantly remodeling expanding and shrinking based on our day-to-day energy demands this requires the development and Retreat of extensive networks of
new blood vessels the human body already contains 60 000 miles of blood vessels imagine how many more miles have to be constructed when we gain weight without angiogenesis without the sprouting of all these new blood vessels we wouldn't be able to add all that fat now do you see where this is all going to expand fat cells release the same kinds of chemicals that tumors do to swell its blood supply fatty tissue is so angiogenic open heart surgeons have even tried grafting fatty tissue directly on the heart after a heart attack in hopes it would
Foster the growth of arteries to bypass the blockages you can take fat samples from obese individuals during bariatric surgery place them on living membranes of fertile chicken eggs and within a week the fat is literally engulfed in blood vessels that may help explain why excess body fat can accelerate cancer growth obesity increases the risk of more than a dozen different cancers increasing the overall risk of getting and then dying from cancer by about 20 percent all those angiogenic factors released from our increasing body fat May spill out into our bloodstream resulting in higher blood levels
among overweight individuals which can then drop back down when we lose weight so maybe we can get the best of both worlds if we treated obesity like a tumor using anti-angio genetics strategies to prevent the expansion of our fat mass in the first place there are anti-angiogenic drugs as well as anti-angiogenic Foods we'll explore both next [Music]
