The Longevity Organ: Why Your Liver Is The Key To Anti-Aging! Siggi Clavien

38 to 40% of the US population has fatty liver disease it's predicted that it'll be 50% by 2040 90% of the people with fatty liver disease was not showing up on Bloods one Tylenol does as much damage to your liver as six pints of beer Tylenol literally dissolves liver tissue more people will die of cardiovascular disease because of fatty liver disease then will die of liver disease because of fatty liver it's the Only organ in the human body that fully regenerates 70% of liver disease in the US is not because of alcohol wow what's it

because of you're listening to the human upgrade with Dave asre this is a special in-person live podcast from my studios here in Austin Texas and you're going to learn about your liver um for me the liver is the funniest organ ever because well there's This show called beas and Butthead and there's an episode where they decide to do insurance fraud and so they you know get themselves in a car accident or something or another but they're so dumb that one of them stands up and grabs his head and says my liver my liver CU he

doesn't know where his liver is and I showed that to my kids and they thought it was hilarious but a lot of people don't even know where the liver is it's on the right hand side of your lower rib Cage and I've got an expert on liver here we just did a liver scan uh for me uh clinical grade one and I have the best score that they've seen ever Clin Tech Al which is kind of cool so we're going to go deep on what does your liver do for longevity for brain fog for Human

Performance and for not dying of the big things that will keep you from living a very long time and he is the founder and CEO of equilibrium labs and they're entirely focused on liver and just Upregulating all the hundreds of things that your liver does for you and I've seen massive changes even some people on my team in just a few months of using the an which is their Flagship supplement uh in terms of going from having liver disease to not having liver disease in a few months of taking a supplement so that's kind of

cool and this is based on more than 20 years of research as a herbologist and just working on liers our guest's name is Sigy clavian sigy welcome to the human upgrade Dave thank you very much for having me here it's a pleasure um one that uh has followed to work for a very long time and has participated and really got into knowing your your community and I have to say that the the biohacking community is probably one of the most fluent in health and in science and Cutting Edge communities out there and it's been a

real privilege to enter into this community oh thank you when You're at the biohacking conference by the way guys biohacking conference.com in April this year in Austin you do a clinical grade liver scan that looks at two variables in people's livers what do you track as the two most important things on that scan and then I want to know what should we be tracking in our lab panels on axo health the two most important variables that fibros scan looks at is stiffness stiffness will be indicative of scarring inflammation or Fibrosis which is a technical term

for scarring within the liver okay the other variable that it's looking at that's critically important is liver fat with the FiOS skan we can tell how much liver fat down to the percentage Point how much of your liver is showing fatty change and then we can use that as a baseline to then make recommendations okay so this is a a kind of a cool test the fiber scan you can do this at the biing conference or at some clinics in The very old days doctors would just tap you all over your different organs because a

healthy liver feels a certain way and then unhealthy liver feels more fibrotic well it's hard to teach doctors that and it's also subject to interpretation and whether your doctor was hung over that day so you have a quantitative scan that tells you very very accurately stiffness and fat in the liver what about the liver Labs people can go to ao. health which is part of Upgrade labs and we send a bunch of liver Labs what are the most important things that you should look at if you get a basic longevity panel that includes liver function

if you're going to be looking at liver liver panel just like the body we need to look at several different things holistically so start with the full liver panel on those the three most important are called a alts and your gamas that's going to be indicative of inflammation there are Enzymes that are inflammatory responses that have caused those so that's going to be a sign uh gamma can also show if you've got an infection as well I think if you're going to look at the liver from a whole part you also want to check a1c's

so glucose that's going on plus your lipid panel which is cholesterols whilst cholesterol arguably is one of the most important molecules in the human body too much of the triglyceride and low HDL can be bad and can also be a Sign of Liver Health it's absolutely true that when you have a fatty liver your triglycerides are going to be high it's also true that when you switch to eating the way I've eaten for 15 plus years now written books about is your liver will become less fatty over time and as it does that it will

release triglycerides so sometimes I'll see people go on a lower but not necessarily zerocarb diet and they start eating more saturated fat and they stop eating seed Oils and corn syrup and fructose and magically triglycerides go up for a month or two as the liver cleans itself out and then they go down and I typically see high HDL which is good and you see low triglycerides which is good and those are the primary markers of things are working nutritionally but if they weren't working talking about a and Al what do those liver values mean so

they're symptomatic signs of enzymes that your liver is releasing in order to Fight inflammation or could be fighting liver damage but they're not indicative of fatty liver hence why you've got 38 to 40% of the US population has fatty liver disease Western world it's predicted in the US and Western Society that'll be 50 50% by 2040 95% of people with fatty liver disease do not know it because it does not come up on a blood panel so if you want to get the full picture you need to do your Bloods and you need to do

a skin I absolutely love That if you do the axo Health Scan and your triglycerides are high and your hba1c is high what are the odds you have fatty liver disease I would say probably 70% plus if you're type 2 diabetics 65% will have fatty liver disease 90% of people that are obese and also 80% of people with gout a lot of people go to gout and they don't realize that is a fatty liver that's causing that what are the problems with having a fatty liver what does it do to you metabolically so Whilst we

got this fatty Li liver epidemic so liver disease as a whole in the last 50 years is up 400% most diseases we've been able to keep a hand on and start to push down liver disease looks like an outlier and it's accelerating even with the most cuttingedge medicine in the world it's accelerating and we can get into the reasons of that later but the first symptoms of fatty liver disease are um brain fog which is The whole connection between cognitive function and liver fat which I love to chat about the other is your cholesterol will

start to get elevated A1C because most of your receptors to deal with insulin are in the liver so as the liver gets fattier its surface area diminishes therefore its ability to regulate and deal with insulin goes down as well wow sleep weight gain that's that's kind of phase one you've got proba fatty liver disease or close to it farther down the Road things as yellowing the skin bloating feet swelling as well generally if you're at that point you've got some serious issues but we're about getting getting ahead of that they call non-alcoholic fatty liver disease

and in my books I talk about two causes of fatty liver predominantly and I want you to either support these or shoot holes in them number one is you may not be an alcoholic but you're having a drink several nights a week even just one Affects fatty liver and number two you're eating too much fructose and I don't care if it's fruit or if it's high fructose corn syrup fructose raises fatty liver true or not true of the 38% of people who have fatty liver in the west how much of it do you think is

caused by alcohol versus fructose well liver disease as a whole you know familiar with sosis when we were kids 6% of people with sosis were non-drinkers 94% were drinkers as of last year that's Tipped it's now 51% of curosis patients are non-drinkers 49% are not 70% of liver disease in the US and the world which is two billion people with liver disease is not because of alcohol that's why they give it the non-alcohol wow what's it because of uh primarily processed foods fructose sugar Pharmaceuticals sedentary lifestyle alcohol while it is bad for your liver the

food industry the pharmaceutical industry and the industrial food complex They've made alcohol the boogeyman will over here that's what's causing it that's in India right very low drinking Persia so Iran has the highest percentage of nafl in the world both countries are very low alcohol that comes down to cheap calories high fructose corn syrup all the chemicals wow what percentage of non-alcoholic fatty liver disease do you think Tylenol causes so Tylenol or uh paracetamol paracetamol in the UK the acetam ofin The main compound in that actually dissolves liver tissue oops so as that dissolves liver

tissue the liver's ability to function goes down it gains more fat and it causes all kinds of liver damage in the UK we actually have a lot of TR transplants probably America as well that are because of Tylenol overdoses I was at actually your conference uh back in um Dallas in June or May and I was chatting with a lady who worked for the um Poison Control in Denver and she was telling me that the number one by a factor of three of chemical overdoses that people have that they're getting around Christmas time is Tylenol

teenagers taking too much and Tylenol literally dissolves liver tissue One Tylenol does as much damage to your liver as six pints of beer wow and if you combine the tyol with six pints of beer what happens then you you've multiplied that and you're going to have a Quantum effect to where you'd probably Cause 20 or 30 times as much damage because they're accelerating each other that's so important so over the holidays if you drink don't take Tylenol and I don't care if you have a headache don't take Tylenol it's not okay absolutely and anything High

inur especially high fructose corn syrup Coca-Cola crazy as it sounds Diet Coke is actually worse for fatty liver than regular Coke because of all the chemicals that are in it wow yeah the liver is inherently Intelligent and it's intrinsic and it will look at threats and it will identify what the bigger threat is sugar and fat it's used to because thousands of years it's been dealing with that and it takes it and what it can't deal with it stores as glycans in little fat pockets but when you start introducing chemicals into the liver the liver

sees that is the bigger threat and will bypass breaking down or metabolizing the fats and the sugars because the Chemicals that are in a diet soda or preservatives or pesticides that is so much more of a threat to the human body that the liver will prioritize that as the danger what effect do seed oils have on the liver seed oils obviously they're carcinogenic if they're heated up too much the process in which they're going through canola oil or in UK we call it rape seed oil terrible D causes all kinds of problems with accumulating Liver

fat uh it's carcinogenic it has oxidative stress aspects to it as well so a hack that I learned actually from a friend of yours that my wife and I use when we go out to eat first thing we do is are you allergic to anything we say seed oils C like food and butter and they will always do that for you and it tastes better and it's better for you exactly it I just tell them steam it or cook it in butter or I don't want it yeah I I don't eat any of those I

Haven't eaten a seed oil on purpose or in a processed food even in 15 years and at all there was one time in the UK I ate a dosant which is a croissant I didn't know they also fried it in canola oil it was damn Delicious so there was that one time and it was accidental and Dave you wa croissant yes European wheat is soft wheat doesn't have glyphosate and if I take enzymes with it I can tolerate it pretty well and it was of course hot in Europe I'm okay with that uh so other

than that and because of that I think my liver is pretty happy tell me what did you see in my liver results so your liver would be equivalent to babies it's incredibly soft it's incredibly pliable very very very low liver fat it doesn't get any better than that and out of the thousands and thousands and thousands of people we scan you had Barn the best scores you've ever seen beautiful that means this Stuff might work and some people say well it doesn't work over time or Dave you're taking so many supplements it's harming your liver

did you see any evidence of that no no evidence whatsoever okay this is why the quality of supplements matters and knowing what they do matters focusing on eating less toxins and frankly I don't care if if man-made them are plants made them or bacteria made them or mold made them I minimize toxins first then I seek Nutrients I do not seek nutrients and ignore toxins which is pretty much the vegan diet which I was on years ago when they would have had a very fatty liver we tend to see fatty liver in uh vegans as

well because a lot of the oils and the processes that go into some of those Foods as well once again it comes down to if you introduce 100,000 chemicals and synthetic things into the human diet in 100 years we have not evolved past that you're overloading the liver hence Why liver disease is accelerating what kind of livers do you see in people on the carnivore diet for long term carnivore diet we generally tend to see uh very healthy livers uh we do see which is interesting if they're carnivore but they're also fasting we're actually starting

to see more liver fat accumulate the reason I think that's happening this is um you know hypothetical but we're looking at hundreds of cases of this right now we Haven't yet to do a study is that when you go into a fasting mode there's a lot of health benefits to it but one of the things is your liver thinks you're in Starvation so your liver will start to store liver fat in case you're starving so I have seen a spike up in that as well but it does tend to balance out over time I wrote

about intermittent fasting the bulletproof diet was the first big intermittent fasting book in a very very long time and people got into It so much they started over fasting so I ended up riding fast this way which was saying guys you shouldn't fast the same way every day and you can over fast and one of the effects of over fasting whether you're carnivore or not your body says oh you're starving let's start holding on to fat and long-term carnivore can also cause insulin resistance which is why I've recommended now for 14 years cyclical eating which

means even if you're carnivore Saturday Morning have at least some fruit or have pancakes made with stuff that doesn't have oxalate if you can find it like rice so do that occasionally because it's that coming in and out that signals abundance supports gal cells in the brain if someone's eating mostly fat protein maybe a few veggies and then once or twice a week they're they have 30 or 40 grams of sugar or 100 grams of carbs what's it going to do to their liver if anything if they're on that Diet their liver is running so

healthy anyway that when it does deal with this it's going to deal with it like a speed bump it's going to process it it's going to get it out and you're not going to cause any damage you need to mix up life everything should have a break no matter what it is you know it's always good to mix it up it's like when you're weight training you kind of want to just change things up to keep the body on on the edge of His toes as a trained viticulturist and somebody that deal obviously all kinds

of Science and with plants stress just like coal plunging or heat can cause growth so you want to kind of get the body out of its comfort zone that pushing the body maybe switching to carbs which throws off the whole cycle will actually create growth the only thing that I've seen I think scientific it's proven that will regrow brain cells is fasting but you have to fasten the Right way might not be the only thing if you want to regrow brain cells you have to increase bdnf and I wrote uh one of my major books

is called headstrong and and bdnf is brain derived neut Tropic factor and or neurotropic factor and what happens is anything that raises that can grow new cells and fasting is a primary way to raise it it turns out there's a coffee fruit extract there's there's Lion's man there's a couple Pharmaceuticals some other supplements And electrical stimulation can all do this so when people are at 40 years as in my Neuroscience Clinic we stack everything we can to increase bdnf oh and what raises it most of all ketamine so we use lowd dose optionally lowd dose

ketamine under a physician's care when people are there in order to create massive neuroplasticity and if you stack in fasting and stack in a healthy liver you're going to get much better results right Yeah absolutely I have to uh really happy to learn something new today I'm going to grab that book my uh Chief science officer is a anesthesiologist and he actually put the first government approved clinic in the UK to use ketamine for drug-resistant um depressants I I know a trauma surgeon in New York University that uses it for children that have had traumatic

to to have their magic to have the separation from their body so that they can do the Surgery comeback to mitigate and minimize the psychological trauma of of a of surgery so there is some great medicinal uses for ketamine so I'm excited to read that book is ketamine bad for the liver yes one of the only negative effects of ketamine even in low doses but in any doses whatsoever it does cause liver damage that being said if your liver is healthy it can deal with it so keeping your liver healthy as your first front line

of defense is the Most important thing always remember I tell people clients this or patients the liver is the master of your immune system we always give glutathion to people when they're taking the low do ketamines it's only for 5 days and haven't had any liver issues with it but glutathion a liver protectant a lot of listeners might I put glutathione into the world of biohacking the very first year I started it because it's so important glutathion is a primary Protector of the liver can you talk to me about what glutathione does in the liver

and different ways to stimulate it so glutathion as you know this is a master antioxidant so it can also affect and help regulate other antioxidants in the body as dealing with three radicals it's so important that in the Deliverance formulation we are doing triggers to invigorate the liver to produce more natural glutathione plus we're encapsulating it nanoparticles so That it stays more bioavailable for about 6 to8 hours glutathione has many many properties and I would say it's incredibly important I if I do do an IV I'll get it done but I try to keep on

my Deliverance to do it and to the best source of anything is to naturally produce more of it but we need other things in as well and I'm intrigued to look at your uh glutathion that you're mentioning my chief medical officer who is a liver and pancreatic surgical Oncologist who left the Cleveland Clinic to come out to now work with us got a PhD in glutathione and its uses in liver repair so we be I want to chat with him about that too it's it's profound and deliverance is the product that you've made with your

20 years of experience the one that just uh healed one of my staff members who went from like stage two fatty liver disease back to none at all in about 5 months of taking Deliverance so the the strategy of Making the body create more of what you want is a standard biohacking epigenetic strategy we change the signals via herbs and other supplements that are part of Deliverance to make the liver do more of what you wanted it to do it's also possible to add exogenous glutathione in and I'd say if you're drinking you probably should

do both or if you took Tylenol because you hate your liver you could do both um what's in Deliverance so Deliverance was 20 years of R&D And it was a combination of traditional herbal medicine and in eastern medicine we have about 5,000 years of Capia so it's a tremendous amount of knowledge and there's 17 active herbs ingredients and they're mostly root based and then we combine that with Cutting Edge Western technology so I took the best from ancient wisdom modern technology to combine those in so we actually look at the molecules Within These plants pull

them out and extract them we look at Bioavailability we're doing clinical studies scientific studies as well and people ask people what is the main mechanism of action well there's lots of mechanisms of action that are happening and I formulate and we believe in root cause medicine is to get to the root cause of it but also in listening to the body rather than having a I think more of an active or a Yin approach to Medicine we have Yang we listen to the body and we support the body to do what It does and we

sometimes you add things to do that such as supplements dietary things as well and no single ingredient is doing everything it has three pillars that it stands on on one is it optimizes liver function everything from metabolizing liver fat increasing blood flow glutathione production cellular growth secondarily on that it's also increasing oxygenation of the blood red blood cell count increase then the second pillar is a neurotransmitter we Have a very powerful neurotropic in it that is increasing neurotransmission which one uh so that is a molecule from called a clonia Cava and there's a molecule that

only exists in this one type of aonia Cava out of juu Island South Korea that cost about3 million in 15 years of R&D to isolate that molecule wow that increases neurotransmission so when you take Deliverance you do get an immediate effect which is the mental Clarity and That's the neurotransmission and this is different than Cava entirely just for people listening this is yours a Cava so unrelated to True Cava which I'm also a fan of for different reasons okay yeah I'm a fan of Cava as well this is a Colonia Cava with the c okay

and it's 150 times stronger than any land-based antioxidant so the antiox off the charts yeah it comes from this but it's only this one type of Kel in the world it's funny I have been taking That for 10 years because I'm into longevity oh fantastic yeah most people don't have no idea what it is we take a th000 kilos we refine it to one kilo and then we get four part distillation we get one gram so we're actually extracting one part per million so that I'm obsessed with bioavailability and quality not quantity it's a million

to one concentrate exactly wow and that's what you feel right away that's also on an orax score it's it's 450% stronger Than Lion's man and it comes from the sea interesting is the it's these 400 foot seelp Forest where it grows and for a thousand years uh the fish that live in these sea Cel forests are some of the most priz and expensive fish in the whole Sea of Japan and the reason is because they're eating antioxidant rich food all day so they're incredibly healthy wow and then the third component of Deliverance is the antioxidant

aspects of it not only is the Antioxidants that are in the product off the charts but we did a clinical study called an AEL rack where we're looking at what happens in the cells post metabolization and post consumption how much antioxidant activity is happening that was also incredibly high and most people get in this Vicious Circle where oxidative stress causes inflammation inflammation causes oxidative stress and you get stuck in this Vicious Circle I'm trying to crack that with Deliverance by Hitting you with so many anti-inflammatories so many antioxidants that you stop that cycle and then

you can go into more of a healing cycle as well the professors at UCL my chief medical officer me and a lot of us we suspect that we're getting into the mitochondria with the antioxidant activity that's one of the studies that we're conducting but antioxidants are incredibly important for dealing with free radicals and anti-aging and Longevity that's uh that's incredible so you're in fact you could test whether you're getting into the mitochondria yeah that's one of the things we've got a bunch of studies we're doing next year that's one of the big ones we're uh

we're looking at yeah there's a collaboration with one of our our speakers at the conference from UC San Diego who makes the the me Health test oh wow looks at mitochondrial function so I'll make a connection please int his Name is Dr Hil Patel and uh I've been to his Labs down there and they're just doing great work on mitochondria and actually measuring them so like that's the perfect test for you when you come to my biohacking conference in May in Austin we're taking over the entire Fairmont you can get a liver scan for half

price when you come in so biohacking conference.com that's savings will pay for a substantial portion of a ticket to the conference so you Definitely want to do that but most of all just try deliverance and go to loveyou li.com and code Dave is there a wearable that would work to help me track my liver I'm testing two different wearable devices now I was CTO of the first company to get heart rate from the wrist I wear levels continuous glucose monitor is that enough or is there some other thing I need personally I wear an aura

ring and I found it to be very useful I like it for Sleep looking at Recovery things like that lingo is the Abbott patch in the UK I really want to get into do a research we're actually studying that as well because as the liver has 500 functions you know everything you eat all the vitamins nutrients all those things they're all stored processed and managed by the liver so as those are checked as those are gone through the body that's going to affect your Readiness score that's going to affect your sleep score all That as

well there isn't an actual wearable that's tracking Liver Health but there are things around that that we could look at got it um I would look at my heart rate variability in the morning if that's high your liver is probably doing okay right you're unlikely to have fatty liver disease and a very high heart rate variability consistently right correct okay got it so if your HRV is low maybe you should look at your liver and how would you go About doing that well one thing is you could get a lab test which is going to

miss some of this you could get a physical scan or if you're on a budget there there's nothing wrong with saying I'm going to improve my liver you go on a supplement like deliverance and you try it for 3 months and if your brain works better and your har variability goes up like great I solved it I love to track what I'm hacking and sometimes it's easy how do I feel right now that's Free did I wake up groggy that's free What's My Morning Readiness score it's a few hundred and you can do it for

years those are affordable but going into a doctor and getting a liver test or doing the axo health panel that takes money so I just want to encourage you if you're young or you're just getting going and you can't lose weight and your Skin's not looking good you have brain fog well you could try taking Liber supplements for a couple months and see if it all Changes Deliverance like I just said reverse stage two fatty liver disease in a few months uh and one of the people I work with really closely so I'm I'm pretty

impressed with the the combinatorial strategy that you guys put together just to speak speak on that too which I think thank you very much for that it's that's why we started the liver clinic so in the UK to get a FiOS scan is a 1 to two year weight list with NHS wow if you go private it's Incredibly expensive you know we're data driven and evidence-based so I don't want to people just to be taking deliverance and saying oh I feel better I don't know if I feel better so I wanted to hit it from

three perspectives one anecdotally how are you feeling how are you sleeping that's just as important as your biomarkers some to some people it's more important let's look at your biomarkers so we ideally get a blood test and a scan you take Deliverance and then we test you again at 3 months and 6 months so the proof is in the pudding and in the data and then thirdly you hit that with scientific study observational studies who are who are the people using your product and endorsing it what studies have you done how much you Sciences behind

it you know what are you using technology what Innovations are you using we use all three of those to try to get efficacy and results I'm trying to prevent people From getting chronic disease so we need to really be getting ahead of it I think it's really important to note and I had it was the head of Cardiology at Mayo Clinic in UK and I was saying you need to be looking at fatty liver for your cardiovascular patients he of course you do he said well there's not not a correlation I said let me get

this straight what are the two main causes of cardiovascular disease he said type two diabetes and metabolic syndrome correct The foundation for both of those is fatty liver fatty liver leads to fatty liver disease and that leads to metabolic syndrome and type two diabetes if you want to look at cardiovascular risk you need to come back and check on your liver Health First by keeping that low metabolic syndrome diminishes type two diabetes diminish and that's really important more people will die of cardiovascular disease because of fatty liver disease then we'll die of liver Disease because

of fatty liver wow that's profound in superhuman my big book on longevity like step one don't die and there's four Killers um other people in the field of called like the four horsemen but I thought that was too much of a cliche so I just call them four Killers so there's diabetes which is a precursor to cancer and a precursor to cardiovascular disease and a precursor to Alzheimer's disease if you don't get those four things you'll Probably live a lot better than you otherwise would have in fact that goes without saying and you're much more

likely to live longer and those are unlikely to extend human lifespan they're just to make sure that you feel good and live as long as you could and then we add in the other true longevity technologies that have already added 6.5 years to the expected human lifespan over the last 25 years and I'm saying that because there are people out there Saying there's no evidence that we can extend human life and I'm like we already did it so if I was to take care of my liver even starting when I'm 20 years old that's going

to shift my risk of diabetes and it's going to shift my risk of cancer and cardiovascular oh and when I won't get Alzheimer's or brain fog which might happen decades before that right and you have better looking skin and better looking hair oh no not that so okay what if I'm on a budget and I like to go out to restaurants every now and then by the way neither of those is true for me I like to cook my own grass-fed riye because I'm really good at it but let's say I'm going back to myself

when I was 25 or something so I said I'm going to take some steps to take care of my liver and that buys me the ability to maybe do some things like have a drink you know eat some french fries is that a good strategy taking care of your liver absolutely as well I Don't know if you'd want to start off by already thinking the naughty things you're going to do you know sometimes the stress of not having the french fries or not having the glass of wine could cause more damage number one damaging thing

in the world is lack of sleep for two is stress then you go through all the carcinogens and everything as well do you do you think people really get stress because they didn't have the french fries some people I think some people do maybe they maybe not french fries per se maybe the AL some people will get stressed yeah because they they calm down it's a copy mechanism social anxiety social anxiety is a great thing um people are learning more though and opening up so they're learning breathing techniques they're learning things to modulate you know

anti-depressants is very damaging for your liver as well what that does is that that robs people that are growing Up of the ability to coping mechanisms how to deal with things right you don't that can cause stress de-stressing and you know there's a lot of things you can do that are free and and I always say the number one thing you can do for longevity and health is immediate and it cost you no money is just be conscious that's the first thing you can do so have you been conscious of I'm taking care of my

liver what am I doing that's going to help to answer your question Absolutely you know drinking lots of water leafy greens just be you know use common sense in what you're eating it's really funny because people enter biohacking usually because whe I just want to perform better at all sorts of things or I want my brain to work or I want to lose the weight the way I've lost the 100 pounds or I want to put on muscle whatever the thing is eventually you always end up at I want to feel good which means I

want to be more conscious And therefore I want to live longer so biohacking is a gateway drug to Consciousness and Longevity and it always ends up there that's why upgrade Labs is structured that way as well because people are going to say you know I solved all my immediate problems I just want to be happy what's that take and what's missing from a lot of the personal development stuff try to be happy when your mitochondria are broken or when your liver can't process toxins Well it's very hard to be happy because you have inflammation going

on all the time then the mitochondria are stressed because they keep getting an inflammatory stress signal and then you're stressed so this is why the primary detox organ in the body to me is one of the most important and I've been I'd say pretty well obsessed with liver function as well as reducing my toxin intake so I'm excreting more and I'm taking in less and over time the effect On longevity on Aging it's really profound on what can happen it's got like Benjamin button's liver there you go you the liver is so amazing it it's

the only organ in the human body that fully regenerates no other organ in the body fully regenerates and it's let's say for instance one of your friends needed a liver transplant that we would do what's called a live liver transplant we would take a third of your liver out we would put that into your friend and That'll grow back to a fully double loed organ and yours will grow back no other human organ does that the average age of your liver is three years whether you're 95 years old or 90 years old or five years

old it's about three it's never older than 10 so it's also one of the youngest organs but if you're constantly beating it up as an ageb when you look at radical longevity we always want to find examples of of times when regeneration is possible and The logo or the mascot for upgrade Labs is the Axel and the Axel is a rare type of Mexican amander relative and it's the only vertebrate we know of where you can Crush its spinal cord over and over it'll grow back any LM you will just go back over and over

it's like Wolverine so that's a proof that it can be done in vertebrates and the liver as you just said is proof that some tissues in our body are fully capable of regenerating do you see a future where we learn how The liver does that and then we Gene edit other tissues so we can regrow them absolutely this right now we know 500 vital functions the liiver does but there are thousands we're learning more and more an exciting part of being a scientist and being involved with Deliverance as that you know we have known knowns

we have known unknowns and there's unknown unknowns that we don't even can't even contemplate yet that's going to come out of that we've also Taken patients that had F3 F4 fibrosis which common old school medicine would tell you is irreversible we've switched that around the also common thought process is that people with sosis cannot be fixed it's incurable I'm working with uh Dr Dio con who I think is a colleague of yours and some other stem cell doctors and we're looking at okay what's the next Generation Let's do let's take stem cells that are programmed

to regrow Li liver cells and liver Scar Tissue Let's ultrasound guide them right into that point let's regrow that area and open up that Canal so that liver tissue you can regrow so Innovation is is incredibly important as the as the liver is healthier everything else is going to be healthier what's the connection between your gut microbiome and your liver you can also say that the liver is kind of the master of your microbiome it's a two-way street off microbiome can Actually if it's off or it's bad or it's at a whack can affect the

liver negatively and also if the liver is not functioning properly its ability to produce BS and enzymes and stuff to go into the uh the gut microbiome is affected as well you know when we eat food gets broken down in the stomach it goes through the intestine the intestines are pulling all the nutrients and minerals and proteins out that goes back to the liver the liver then manages Ages those stores those so if your gut microbiome is out of whack you're not properly getting absorption which a lot of people I think that's a problem with

a lot of people taking supplements that's not being absorbed so you've got to fix your intake so that your liver can then if not you could be starving your liver of minerals even though you think you're eating everything great it's incredible what happens if you have bad gut bacteria because they block Absorption they also make one of the biggest toxins that affects brain health brain fog systemic inflammation and even Liver Health and it's called lipopolysaccharide or LPS talk to me about how LPS gets into the body and what it does to the liver so as

obviously it's it it's produced and created as an offset some of the most toxic things that we deal with are actually byproducts of breaking something down that gets into the liver It affects liver functionality and the just as there's a gut brain axis which is more to do with emotions there is a liver brain axis as well it has proven I just read a great NIH AG study I was reading some stuff out y the other day if a liver has too much of that what will happen is it can go into the brain and

it'll diminish cognitive function it is proven that fatty liver disease affects cognitive function full stop some of those chemicals especially the Ammonia that comes as a byproduct of breaking down proteins that actually can get up into the brain if you've got fatty liver cross the bloodb brain barrier and actually cause decrease in your brain matter it can actually shrink the size of of your brain ammonia is interesting because if you're on a high protein diet and you don't have enough stomach acid or enough digestive enzymes or you have gut if you have bad gut bacteria

you will make ammonia and You'll smell it because you'll have bodybuilder farts that'll be terrible and that ammonia causes profound brain fog so that is a state you don't want and these lipopolysaccharides are bacterial toxins and they're really bad for the liver so if you have gut disbiosis or if you have an infection somewhere in the body the reason you feel like crap is that these toxins are produced and in a normal healthy gut with an intact lining which few people Have if they eat the normal Western diet the lipopolysaccharides stay in the gut and

get excreted but since most of us have some degree of leaky gut the LPS toxins enter and they go to the liver so one of my strategies for longevity is well what protects the liver from lipopolysaccharides glutathione so Deliverance your product raises glutathione in the liver which helps protect you and interestingly this weird thing called C8 MCT oil that I turned Into a billion doll industry in studies it protects the liver from lipop polysaccharides what takes these toxic compounds through the gut lining is saturated fats including lauric acid which is one of the MCTS and

there are Brands like on it who say oh we have lauric acid lauric acid is an abundant and cheap MCT so cheap that some places they use it for fracking but you can claim it's an m C it's the one that escorts LPS across the Gut the most so the strategy for me is understand that I'm going to eat a high saturated fat diet because that's good for me that means I need to have healthy cut bacteria but I might not because something in my last meal could have thrown them off so what do I

want to do I want to protect my liver by making sure that it's producing enough glutathione so that the normal amount of LPS and the normal amount of environmental toxins I can't avoid they Cannot touch my liver and as result of this strategy for more than 10 years I have the best liver score you've seen out of thousands and thousands of patients so I think it works at this point is there anything else you would do for that strategy besides saying I mean really well hydrated I mean as you said got a lot of ways

that people's got microbiome gets completely devastated is antibiotics and in the west especially in America they tend to over subscribe Antibiotics where they should be giving you a probiotic in tandem with that so I would think get ahead of it keep get your gut microbiome try to make sure that's imbalanced as much as possible so that a your liver can do its job and because you're doing all these preventative issues and you're keeping all these mechanisms these Pathways these flows really healthy is indicative of obviously Your vitality and also your amazing liver score understanding that

You can make toxins on board and if you ate something and you have stinky farts that means you're making toxins just unequivocably so what should you do well you should always have adequate glutathione in the liver when Deliverance does that you might also take activated charcoal away from supplements when you have bad smelling farts because it's going to bind to the toxins in the gut and you know they're there because you can smell them so when That happens well you'll fart less which is good for the holidays unless you don't like your in-laws or something

then that also though means less brain fog because it means less of these toxins could cross the blood brain barrier so this idea of eat less toxins produce less toxins if you're going to eat toxins or you are producing toxins block them and increase your ability to get them out of the body and that leads to more Consciousness happiness less Pain in the body less risk of dying from all the different ways you could die and then maybe you'll live longer but there's something we haven't talked about that has a lot to do with the

liver coffee is coffee good for you coffee is very good for you coffee in its basic form is a is a berry you know that Berry's Tak it's picked it's cultivated it's loved it's roasted and then it goes into this this antioxidant drink that we drink all Over the world coffee brings blood into the liver which is very important that's why being hydrated is very important you want to keep the body well hydrated whilst there is a aspect of coffee that takes some water out coffee is very very high in antioxidants there were some studies

I was reading with NIH studies this is all available on PubMed that people that drink two cups of coffee a day or more are 44% less likely to get get Curosis this is a you can pull this up everybody but Pub Med and people that drink four cups of coffee a day are 65% less likely to get therosis it lowers your chance of fatty liver disease it lowers your chance of liver disease as a whole carcinogenic aspects of it cancer the effect and the correlation between drinking a lot of coffee and liver disease is undisable

so coffee protects your liver from all sorts of bad things okay that's cool that and it promotes Your liver it's getting more blood in there it's getting antioxidants in there it's supporting it as well it is which is one of the reasons I think it's a preeminent longevity substance now there's a little bit more to coffee though you mentioned the potential for dehydration and caffeine by itself is such a weak diuretic that it doesn't count for making you uh lose water but if there is mold toxin in coffee which is a bladder toxin when people

drink a Cup of coffee an hour later they're a little jittery or cranky but you have to pee and your bladder's not full that's dehydrating you because the body is responding to the Toxin and the toxin from mold that's in the coffee makes the bladder irritated so the body will pull water out of your blood that's what's dehydrating in order to dilute the Toxin and then it makes you feel like you have to pee even though your bladder wasn't full so it turns out coffee that makes You have to pee is not good coffee and

coffee bi it itself in studies actually does hydrate you as well as plain water except plain water isn't very hydrating because it doesn't have electrolytes in it so what do you do about that well there's this little thing called danger coffee my new coffee company and it is coffee that has no mold toxin in it and it has electrolytes and trace minerals in it which makes it more hydrating than coffee without those things so I'm Looking to solve all those problems but the Smoking Gun in the room for Liver Health is mold toxins what do

mold toxins do to Liver Health very interesting brought that about danger coffee I have to speak on that I didn't understand the the level of sophistication danger coffee till we were at your conference and my wife and I bought a huge bag we've been taking it since and it being mold free was one of the biggest selling points that I'd Never seen that before and that's why that's actually what we take at our house um we love coffee there's so many different forms of mold and there's so many different effects mold can get into the

obviously it gets into the bloodstream both Airborne touch it could be on your food as well and different molds of different levels of toxicity so you start to overload the liver and cause liver damage the liver is constant repairing that can also get Into the blood and it can affect blood cell count it's weakening your immune system causing fre radicals to cruise around causing oxidative stress you get inflammation mold is it it could affect everything to where um I mean people that have cancer might have we have a loved friend that we think didn't live

as long because there was mold in the house she was living in and her immune system was being attacked constantly by the mold so mold is and it's a huge Problem and it's one that's I think tend to be overlooked and landlords don't want to deal with it environmental mold or mold in food or mold in coffee they all affect the liver one way or another and a lot of the worst mold toxins are called xenoestrogens and xenoestrogens are either man-made like Plastics or BPA and things like that or they're made by primarily toxic mold

and one of the nastiest ones is called Zerone and it's such a powerful estrogen that is 10,000 times stronger than human estrogen and if you live in a house with zerone which I did when I was overweight you can get fat on 30% less calories and it's so powerful that if you eat conventional meat there's a good chance that the Industrial company that owns the cowl production facility they put this estrogenic toxin into the cows so they can feed the cows 30 % Less in other words food cost goes down and they Feed you a

cow that has levels of estrogen that you shouldn't have what organ in the human body clears excess estrogen and Plastics out of the body the liver oh what do you know that's crazy you just told me that that's terrible it is terrible um the drug for people who are doubting me it's called zerinol and ranchers do buy it and I don't know it's at least 25 million a year in Revenue probably more uh for that which should be banned immediately But there's a lot of other things like atrazine which is in most countries it's banned

in the US it's not banned it disrupts human hormones in fact at levels that are allowable in water it causes frogs to become hermaphrodites what does the liver do to remove atrazine so anything to do with toxic that's coming in that's not natural anything in the body actually the liver is dealing with it managing it breaking down and synthesizing it um and if you Felt you were exposed to that I would like you brought a good point earlier with activated charcoal if ever Anor gets food poisoning or bacteria first thing I do is tell them

besides drink lot of water get activated charcoal CU that's going to bind and help to get that out as well but if your liver is fatty remember it's not functioning as well and if it's not functioning well its ability to get those toxins out diminishes therefore you could Exasperate the problem as well the goal of biohacking is to build highly resilient people um in fact danger coffee is called danger because who knows what you might do it requires resilience and if you want to have resilience the number one organ is your brain the number two

organ is your liver because your liver is what controls how well your body gets rid of toxins and if you don't get rid of toxins very well your brain is cooked and as someone Who's had profound problems with toxins chronic fatigue syndrome serious brain fog every bad thing I can think of has happened at one point or another it really does come down to your gut disbiosis it comes down to your liver it comes down to taking in less toxins and excreting them better even something like man boobs every guy in my family has them

and I had them to the point I was really self-conscious about it and at this Point I've been in you men's magazines you know Fitness magazines with my shirt off without fasting and all that crap ahead of time and I don't have man boobs the vast majority of the time if you give me enough mold I'll grow them back but it comes down to liver because if your body has enough test testosterone it's likely to turn it into estrogen and what removes estrogen it's the liver so if you're on testosterone replacement therapy which you should

be if you're a Guy and you're over 30 and your lab tests are low and yes you can test that at axo Health which is very very low cost if they're low you need to either change your diet change your sleep change your exercise and get your levels up to 20 of free testosterone if you can do that by yourself power to you but given the toxin environment we swim in you probably can't if that's the case and you go on testosterone or even if you don't support the liver so that you Get rid of

the estrogen otherwise the more testosterone in your body the more estrogen you'll make and then you can be on testosterone and still grow man boobs my body is uniquely good and making estrogen out of testosterone so what do I do to not get man boobs I keep my liver running Hormone Health is incredibly important I was just giving a talk at um big Medical Center in London on menopause and some of these were doctors practitioners patients as well And I asked her said what is everybody doing for Liver Health to manage your menopause just like

testosterone to men menop to women the liver is in charge of your hormones it's synthesizing them it's creating some of them liver is also a gland it's an organ Ander gland and bad liver or liver that's not functioning as well can dramatically affect early menopause per menopause estrogen and progesterone getting out of whack and with the prevalence of HRT Right now where the they should be doing bioidentical plant-based hormones to just join everybody on HRT plant-based is not bioidentical which is it no there's bioidentical plant-based hormone therapy for women but if it's plant-based it's not

bioidentical right CU cuz humans are plants so if it's plant like wild yam can't even convert into progesterone they well they identify that the the plant-based hormones that will go with the the Patient much better and you have a lot less side effects the cancer s side effects to the cancerous growth maybe have the terminology wrong gotcha um I bioidentical I would support um most of the plant-based hormone supplements you see out there they're fake because the body cannot convert wild ym into anything it takes seven steps in a bioreactor to make Yem into progesterone

so I would just say bioidentical and if they derive it from plants or from Fermentation or from anywhere else don't use the stuff that comes from pregnant horses which is what big farmer wants to sell you yeah or dairy cows and stuff as do as well gotcha functioning liver healthy liver is going to make menopause symptoms much more dram much less dramatic much more balanced mood swings the sweats as well if you if you in the menopause or type type two diabetes you got to start with the liver as well it's incredibly incredibly important o

talk To me about menopause or param menopause in the liver so as the liver manages synthesizes and controls liver if your liver is not functioning very well its ability to flush out the old hormones and to go through the cycle of Rejuvenation and this you know incredibly important part of woman's life its ability to do that decreases it's why women between ages of 20 and 45 that drink three times a week or more socially are 30% higher chance of Getting breast cancer and that is because their liver is not functioning as well its ability to

get rid of and flush hormones goes down those bad hormones sit those build up those can then metastasize and turn into cancer so there's a direct correlation with alcohol which is toxic a woman that's taking it isn't drinking as much and functioning as well therefore causes all kinds of damage Downstream one of the interesting things around Param menopause is that the liver amongst its 500 plus things is it converts progesterone into cortisol yep now you might say well that's a bad thing except low cortisol is four times more dangerous than high cortisol so what that

means is you may have a dysfunctional stress response in param menopause if you have a dysfunctional liver so you want the body to be able to call for cortisol when it needs it and for the body to not need cortisol Because you've managed emotional stress and environmental stress and sleep and all of that so this is a little known part of param menopause is have a healthy liver so your body can even if you're taking Progesterone can at least convert it into the downstream hormones that it needs and the liver plays a central role in

that so if you're dealing with really really harsh param menopause look at the liver and deliverance would be a way to do that Absolutely no organ in the body is managing your hormones more than your liver and one of the big studies that we're doing next year is type two menopause I'm sorry type two diabetes and menopause those are the two areas that we're going to go into because it's liver Centric beautiful you brought up a good point earlier with type two diabetes there's a silver lining to type two diabetes and fatty liver disease they're

both reversible they are so many Things that are irreversible are totally reversible when you stop listening to Big Pharma all right thinking I got a serious L question for you yeah in front of you is a giant plate of french fries cooked in a mix of canola corn and soybean oil at a restaurant and a cigarette you have to eat the frenchis or smoke the cigarette which one are you going to do I'd smoke the cigarette cuz I can get those toxins out quicker exactly you get at most 24 hours of Inflammation from the cigarette

and by the way smoking is really bad for you micro do nicotine good for you for longevity but those french fries they're going to trash the liver for several days right they're going to trash it for several days they're going to be stored in the fat you're going to have fat issues you're going to be dealing with that plate of french fries for weeks potentially months yeah that's why I just don't eat restaurant fried food Ever and by the way fried Brussels sprouts french fries I don't care same thing I if it's deep fried don't

eat it yep carcinogenics what do cooked in what else was cooked in there mixed with it too yeah it's just not a not a good way to go and by the way there's a get out of Gil free card for this if it was fried in beef Tallow I I would not smoke the cigarette I would eat the french fries now what what does pharmaceutical nicotine things that use like a spray or A lozenge what does that do to the liver well pharmaceutical nicotine is obviously much less dangerous than smoking it it does increase toxicity

if you mix it with alcohol so you're taking something that's toxic and you're doubling down on it okay so it makes alcohol worse correct okay it doesn't show a direct correlation between liver enzymatic reaction or diminishing liver function but it has been shown to also reduce bof flow and bof flow is Incredibly important part of the body and how break toxin and Foods them got it the studies that I found showed it was a a minor reduction in bof flow and for people who read the bulletproof diet I talked a lot about how important increasing

bof flow is and to be clear I recommend about 5 milligrams of pharmaceutical nicotine a day as a longevity strategy because people who smoke don't get Alzheimer's or Parkinson's they just get cancer but If you use nicotine without using tobacco without burning stuff and breathing it then you don't get the canc cancer risk so this is one of those neat little neutop things and at those low doses it's unlikely to affect bile but what I'd like you to do is tell me what bile does and why it matters and the role of bile in having

a healthy liver so the bile is managed and also a lot of it is processed within the liver but the gallbladder processes a lot of it as Well and the gallbladder acts like a carburator and that will release bile into the stomach at certain times to help down with to manage acidity break Foods down break toxins down as well so having a healthy bile is incredibly important I'd be remiss if I didn't mention that we've seen a huge uptick and I'm part of a big European study that people that have had their gallbladders removed or

seeing a huge increase in liver disease as well as Liver cancer about 10 years down because if you take the gallbladder out which modern medicine has felt that it's cheaper and less expensive just to pull the gallbladder what you've done is you've taken out your control mechanism that the liver uses so now and you've got a constant drip of BS and acids into the stomach which can cause all kinds of effects and Upstream up into the liver therefore increasing chances of curosis any patients that we have come in that Have Nash which is non-alcoholic steatosis

hepatitis which is the precursor to curosis and is very bad damaging first question we asked them do you have your gallbladder so if you don't have your gallbladder it's incredibly important that you're taking extra care of your liver getting a scan regularly as well one of my really close friends for 25 plus years had our gallbladder taken out years ago so I did a lot of research and the biggest thing You could do is make sure you take Ox bile with any meal that contains fat to help the body be able to metabolize fat because

fat contains fat soluble nutrients and it is a nutrient itself and without a gallbladder you're not very able to digest fat you're can have greasy stools so Ox bile is something you take with every meal for the rest of your life if you've had your gallbladder taken out and you sort your liver with the right herbs Deliverance is a great Way to do that and then you get a regular liver scan because you are at increased risk for that much bigger risk for Nash and liver cancer as well that Ox pile thing as well we're

going to we're going to look into that probably add that to our protocol we a lot of patients that come in so with the liver clinics our goal and our promise is we will hold your hand whether it's as little as nutritional advice all the way up through Deliverance scanning MRI Biopsy if needed or up to liver transplant we're going to make sure that you're taking care of it the best way possible and you know being conscious of your liver what you're eating what you're drinking drinking more coffee avoiding toxins doing these things as well

so I think that's a really interesting protocol that I want to uh I'm going to add in I'll speak to Dr Gareth oxp is there a particular brand you recommend Or uh is it liquid or powder I don't know much about it it's just capsules that that you get so a lot of brands of digestive enzymes include some because even if you have your gallbladder having extra Ox along with extra protein digesting enzymes it actually helps you absorb your food better so if you don't want pneumonia and you're on a carnivore diet or just getting

adequate protein I recommend one gram of protein per pound of body weight and that is animal Protein not that fake plant protein that's you need three times as much of that no one can do that without farting all the time what that means is take enzymes with your meals and then you get full benefit of the meals and if the enzymes have Ox bile in them or you take Ox bile separately then you end up having kind of a superpower for making sure you absorb all the nutrients from your food the other thing and this

gets a little bit technical but it's really Important if you've had chronic faat syndrome um or you've had toxic mold exposure somewhere around 25 to 30% of people have genetics that means we evolved when there was a strong benefit to being able to go to a neighboring Village or country take a couple arrows or cuts from a sword and clot quickly not get infected so strong immune system strong blood clotting and the ability to go without food for substantial periods of Time because you're basically Marauders you're like oh let's go invade a village need everything

go do it to the next one and not get sick and not die so if you have those genes this is on HL drr if you're into genetics that means that your body recycles your bile which is great if you're going to be fasting and there's famine because it's very expensive to make bile in the liver this biologically expensive the only issue is bile contains all of The fat soluble toxins all the pesticides all the microplastics all the BPA all the synthetic estrogen that that is made by man or by mold so we tend to

accumulate toxins and by increasing bile flow that means we poop out more bile and so if you've had one of those diseases or you have ancestors who pretty much were gangsters then what You' want to do is you'd want to take more Ox bile and you'd want to protect the hell out of your liver because if You do that you're much less likely to fall into systemic inflammation chronic fatigue syndrome and all the things that come with that all of which I've dealt with in my you know being at 300 lb and from going from

there to where I am now with the healthiest liver you've ever seen if I stop taking care of my liver I'll start gaining weight and I'll start getting brain fog and then I'm less resilient to toxins and then I need more sleep and then I have less mental focus And it's just a slippery slope and I really am mitochondrial Centric which means I'm gut bacteria Centric which means I'm liver Centric and all of those are precursors to being brain Centric I just want my brain to work but if the underlying things that get rid of

the toxins that stop my brain from working if they're not working I'm not going to show up the way I want for you know for the podcast or for my kids or any part of my life and that's why I think this Is a really important episode incredibly important we were at uh talk to JP Morgan in London I was also at Formula 1 uh race team spent a billion pounds a year on their team and we went to scan their engineering department my wife and I and after getting done scanning we said okay the

national average in the UK is 38% 50% of your men in the engineering department have fatty liver disease that means 50% of your engineering department are cognitively Handicapped as I said there's NIH AO studies on this if you have fatty liver disease you are not operating in 100% cognitive function uh with um Dr Porter for brain Tab and we're describing this is you're in a neuroscience if you want to have a better working brain you need to look at what's happening with your liver an obese child will always score less than a thin child on

cognitive test because always generally most of the time not always yeah I don't believe in Definitives either but bad n clature but essentially fatty liver cognitive function right and when he told JP Morgan I said you have guys out here making billions and billions and billions of pounds of Trades a day and they're not operating 100% or cognitive function it's kind of funny back when I was first starting bulletproof and for new listeners I have nothing to do with bulletproof anymore but it was called the bulletproof executive and I got my Seed Capital by flying

around the world and meeting with hedge fund managers including a JP Morgan to teach them how to have brains that work better it was cognitive enhancement and I taught some of them how to manage their stress response better so they can make better trades and it it's funny but that was the the first probably between and $100,000 that I used to start the company came from Consulting for hedge funds on cognitive function and a 1% Change in cognitive function for a guy trading a billion dollars a day is massive it just takes one little shift

in in a decision and in Formula One you're driving $100 million a car and you have that 0.01 second difference in reaction time it's important and you talked about engineers um I was an engineer at one point in my life Engineers usually have circadian dysfunction we're staring at screens late at night and there's a way to fix That it's called true dark glasses you can also just turn down the thing you can learn how to go to sleep better but in racing and in certain industries your exposure to petrochemicals is very high if you're exposed

to petrochemicals what will it do to your liver it will overload the liver with toxins as again some of these go they get into the brain they crost the cross the bloodb brain barrier and they can actually deteriorate the amount of brain tissue You have so your first line of defense is your liver we've had people come in with sever severe liver scarring and liver damage that worked at the airport like baggage handlers people that are outside around that all the day people that work in tunnels um policemen on the streets you know they're one

of the biggest ways we get toxins in is breathing it as well it's not just eating it why are Indians more likely to get fatty liver disease so people from The subcontinent India Pakistan Sri Lanka Bangladesh that kind of Crescent right there they have a genetic adaptation to where they store liver fat much faster than other ethnicities do and that is because in that Society in that part of the world they go through periods of famine so they have have genetic coding through basically Evolution to store fat on the liver so that they can get

through times of famine and that switch has not been shut Off because of time therefore they're getting fatty liver much much quicker and are three times as likely to have fatty liver disease than a Caucasian or an African or a lot of other ethnicities hence why di type two diabetes is so high in those populations one in three people at least they think it's closer to 500 million in India have fatty liver disease wow it's really 50% is probably more likely the answer for this would be intermittent fasting or you could do What your grandmother

told you to do if you're from India eat ghee instead of these weird fake American oils ghee is protective of the liver from fatty liver it's the bad oils it's the corn syrup it's eating late at night and it's not fasting the way your ancestors did because there was no food for periods of time so if you are from India or from that part of the world from Pakistan just anywhere in the Fertile Crescent there you're at much higher risk than The rest of the world but it's an easy thing to fix earlyer dinner turn

the lights off at night or at least turn them down don't eat seed oils eat more ghee you'll like how you feel which sex is most likely to get fatty liver disease Men by far 2third of people with fatty liver disease are men one3 are women just the genetic makeup of men are different therefore they store fat longer they get more of it and they have fatty liver disease quicker that's Incredible the turns out 2third of women are Alzheimer's patients so that means women are twice as likely to get Alzheimer's as men and men are

twice as likely to get fatty liver as women 100% okay so for guys we got to protect our liver and for women we want to protect our brains or these These are risks for everyone so maybe all of us want to protect our liver and we want to protect our brains on the brain stuff uh I recommend my book headstrong where it Talk about everything you can do for the brain and when it comes to liver Deliverance which is the supplement you make has really good clinical studies backing up the fact that in not very

much time it can reverse fatty liver absolutely and we're a great and good company so I think it's important for anybody out there to know that if you're a policeman fireman member of the military a teacher we will we will treat you at a cost and if anybody's Undergoing chemotherapy or cancer we will treat you for free well I think we made a pretty convincing case that having a higher performing liver makes you smarter Stronger Faster more conscious and that you'll live longer as a result of that which is why when you're allocating either your

time your energy your amount of suffering you're willing to under undertake in terms of inconvenience or pain and the amount of money you're willing to spend investing In your liver is a really good idea because it's foundational much like mitochondria like they affect everything so get mitochondria working get the liver working oh if the liver works better mitochondri work better they go together and if the mitochondria work better the liver works better so do those two things and you'll find that maybe like me you can have the best liver score they've ever seen or at

least one that's way above average which Means you'll perform above average you'll probably sleep better and you'll just be less tweaked which would be really cool so sigy thank you for coming in and being on the human upgrade and teaching people all this stuff about the liver which is maybe an uncelebrated organ it's an uncelebrated organ it's one of the ones that's misunderstood and I we also need to add vanity to that list your hair and skin is indicative of your liver Health one of our largest Reseller categories besides functional medicine doctors is actually estheticians

no you want to have beautiful skin and hair which we all do you need to take care of your liver in order to try deliverance and learn a bunch of stuff about your liver go to loveyou.com and as usual I've asked for a discount for you and the code is Dave and they'll save you some money I only talk about things that I've used things that work things that have good science Behind them things that have good people behind them and there's a lot of stuff in the bio acing world you do not have to

try everything this is foundational and it's something that's worth a shot see what happens when you do it I'm always looking at the ROI on your investment and things and I think Deliverance is something that's worth trying if it works then keep doing it and if it doesn't work then stop doing it that's what biohackers do I think You're going to like what you feel see you next time on the human upgrade podcast