I haven't seen any medication that actually has such a huge reach as well as consistency and Effectiveness with these GP Agonist like th appetite and like boto despite the fact that they are medications I mean who wants actually quote like medications necessarily to jumpstart your life right or change who you are but I think the stigma of the days in which we say oh yeah you know like medication is bad for you I mean we know that 40% of adults are actually on anti-depressants a lot of times you need that positive reinforcement to actually be motivated to actually make those changes hi everyone my name is Pauline I'm from Wave Plastic Surgery um today we're going to be talking about Trippe Tite um and we're going to be joined today by none other than DrPeter Lee hello I'm nervous DrLee you don't have to be no no okay just let talking have you done podcast style stuff before me neither well there's always the first so how did you get like uh recruited for this you know I have no idea I was uh volunteered I Alan called me I was in Roland Heights and he was like hey Pauline are you busy I'm like no we're doing a podcast I'm like me okay so first let's talk about triti as a plastic surgeon I mean we deal with obesity all the time right as well as chronic disease um I think um in my uh career right I haven't seen any medication that actually has such a huge um reach as well as consistency and Effectiveness um with these gp1 agonists like THS appetite um I haven't seen anything like that since like B really yeah it just seems like it works consistently on everyone yeah I mean some people have some side effects and we can talk about the side effects a little bit later but you know some people you know do develop side effects but on a consistent basis that side effect is certainly rare and mild and but the effectiveness is just so real yeah and tangible right I myself took mararo or tripati for about a month month and a half or so um side effects wise I it was very mild it was more gastrointestinal related issues for me it was a little bit of nausea but another biggest one for me was um fatigue yeah that was the biggest one I was so tired all the time um but yeah overall I lost maybe 12 to 15 pounds MH on it so it's amazing life changing honestly were you able to keep it off yeah yes I was but you know that's with like Lifestyle Changes too you can't go into it thinking like okay this is the magic drug this is what's going to fix my weight problem I think for me I used it as like kind of like a jump start yeah I used it as a jump start and then from there I just tried to keep the weight off working out a little bit more consistently eating a little bit better because I would assume like if you went back to your old way the weight is going to go back and I think that's what a lot of the people you know are wondering about is if you are is this a lifelong medication do you have to be on it for a long time or like does the weight bounce back if you're off of it what are your thoughts on that I mean there's no question that uh if you stop the medication um the the effect it has obviously you know goes away right um having said that though I mean if you look at the people who has been on th apetite um and in our uh clinics I mean that's what we actually focus on because know th apetite just seems to be U much more effective and like I said you know more consistent uh that works on everyone versus uh the semi glue typ right right um but certainly I mean our patient base are not really necessarily taking it for necessarily medical reasons and in fact I mean a lot of our patients um don't really even fit the criteria uh criteria of morbid obesity right I mean morbid morbid obesity being what I mean we usually talk about like BMI of greater than 30 or like BMI of what greater than 28 I believe with Co with comorbidity right you know with other medical problems but um I mean a lot of our patients um probably not like you okay uh who's uh looking to like uh you know lose like maybe 10 15 pounds but a lot of the patients you know are not that morbidly obese that just no wants to really kind of lose that 20 maybe 20 pounds or so right a lot of the patients U you know who took it for maybe like three to six months I mean they are able to actually kind of keep it off keep it off yeah right and I think uh there is something to be said about um positive reinforcement and I think that's what's missing a lot of times right when you do something and let's say you don't really see the result right uh or at least it takes so long you know for that for you to really realize and be rewarded with that result a lot of times like uh you know you lose that kind of um that that motivation right whereas with uh something like his appetite right mean you take it I mean you said you only took it for like a month or a month and a half right and you lost what 10 to 15 pounds I mean that's significant yeah right and when you see a result like that then I think U you know people because you know they see that result and they're happy with that result um that they're motivated to actually truly do change that lifestyle right to keep it off I don't want to pay more money to do you know so the best way to do it is really lifestyle change right you know you know we've been preaching like I said you know at the start of this this this conversation right and I said you know like we've been preaching for a long time right about diet and exercise and things like that but a lot of times you need that positive reinforcement to actually be motivated to actually make those changes right that is true and I think um you know these um you know medication I mean despite the fact that they're medications I mean we don't want who wants actually quot you know like medications necessarily to jumpstart your life right or change who you are but I think the stigma of the days in which we say oh yeah you know like um you know medication is no longer medication is bad for you right so I mean we know that 40% of adults are actually on anti-depressants right and so I think like there is an acceptance now right that you know medication actually can help your lifestyle right and uh you know if uh Mo if obesity is an issue right you've been trying to actually take that weight off but you couldn't hey you know like if you could take the medication for you know three to six months and really kind of jump start that positive reinforcement I mean I think I think I think I think that's actually yeah I mean I think there is something to be said about that and a little backstory I did try to like before actually going on the medication obviously I did like my d diligence that I'm actually working out and like eating healthy but that 10 lbs just wouldn't you know shut off and so that's why I decided to do Tri of medication and it worked really really well all right so what are the side effects that we've seen um with people taking mojarro you know you started talking about your experience right I mean you talked about nausea and fatigue right um and and you're right like uh the most common effects are gastrointestinal related okay and it is something like nausea vomiting constipation or diarrhea okay I mean consistently it seems like it's those four elements uh that some people may experience some people actually don't okay right uh some people also talk about and especially if they have problems with like acid reflux sometimes like you know that becomes a little bit more manifested it seems like um but certainly not not really so severe although there has been cases of people who have experienced U kind of a severe um symptoms um what would this severe symptoms be yeah I mean it is like things like nausea and vomiting okay some people have experienced uh significant vomiting episodes um so that they you know like when you vomit a lot uh you know you can become dehydrated right and so you have dehydration symptoms right that may require you know some intervention like the like rehydration and so forth is that cor like is does that have correlation with the dosage that the patient is taking right I think as you increase in dosage your symptoms become a little bit more prevalent absolutely okay I mean what we noticed was um and and they come in uh different dosages um and it does seem like uh it is correlated with a higher doses so the lowest dosage is 2. 5 it goes to five 7. 5 10 and then the highest dose is s or 12 or sorry 15 milligrams is that correct yeah uh and you're right like uh because of that um when we're prescribing C apetite uh for weight loss uh we do want to start slowly and So like um you know probably somebody like you we would want to start like at the lowest dose like 2.
5 milligrams like Curious like what dosage did you take I did the first week I did 2. 5 following week was another 2. 5 and I did five milligrams the third week and another 5 milligrams the fourth week okay so I stayed on the lower end of it and I was so I would have lose you know a significant amount of weight it seems like you condensed it in a short period of time right although for most people um they would actually be on the same dosage for for that full four weeks right right so um like like for you kind of like a standard know dosage would be to put you on 2.
5 milligrams for a whole month yes for the whole month and then on the second month maybe go up to five right and then if you want to just do a thre Monon uh treatment then kind of taper off at 2. 5 the third month right them then stop so you go first month would be 2. 5 5 milligrams in second month and then taper it down back to 2.
