Oprah Winfrey on How She Found ‘New Freedom’ After Weight Loss

♪ ♪ >>> WE ARE BACK WITH OPRAH WHO >>> WE ARE BACK WITH OPRAH WHO IS LIVING HER BEST LIFE RIGHT IS LIVING HER BEST LIFE RIGHT NOW, AND ALWAYS, AFTER DECADES NOW, AND ALWAYS, AFTER DECADES OF STRUGGLING WITH WEIGHT, THE OF STRUGGLING WITH WEIGHT, THE TV ICON SAYS IT ALL CHANGED WITH TV ICON SAYS IT ALL CHANGED WITH ONE AH-HA MOMENT. ONE AH-HA MOMENTNT. >> SHE TALKS ABOUT IT IN HER NEW >> SHE TALKS ABOUT IT IN HER NEW BOOK, "ENOUGH: YOUR HEALTH, YOUR WEIGHT, AND WHAT IT'S LIKE TO BE FREE.

" FREE. " WE WILL CHAT IN A MINUTE. WE WILL CHAT IN A MINUTE.

FIRST, MORE ON OPRAH'S'S JOURNE. FIRST, MORE ON OPRAH'S JOURNEY. >> AS LONG AS SHE'S BEEN IN THE >> AS LONG AS SHE'S BEEN IN THE PUBLIC EYE, OPRAH WINFREY HAS PUBLIC EYE, OPRAH WINFREY HAS BEEN OPEN ABOUT HER STRUGGLE BEEN OPEN ABOUT HER STRUGGLE WITH WEIGHT.

WITH WEIGHT. FOR 25 YEARS SHE BROUGHT VIEWERS FOR 25 YEARS SHE BROUGHT VIEWERS ALONG ON HER JOURNEY OF DIETING, ALONG ON HER JOURNEY OF DIETING, DETERMINATION AND DOUBT. DETERMINATION AND DOUBT.

>> I DON'T KNOW IF THERE IS >> I DON'T KNOW IF THERE IS S ANOTHER PUBLIC PERSON WHOSE EN WEIGHT STRUGGLE HAS BEEN EXPLOITED AS MUCH AS MININE OVER EXPLOITED AS MUCH AS MINE OVER THE YEARS. THE YEARS. >> NOW AFTER YEARS OF >> NOW AFTER YEARS OF SELF-BLAME, SCIENCE AND RESEARCH SELF-BLAME, SCIENCE AND RESEARCH HAVE LED OPRAH TO A NEW HAVE LED OPRAH TO A NEW UNDERSTANDING.

UNDERSTANDING. G. OBESITY IS A CHRONIC DISEASE, OBESITY IS A CHRONIC DISEASE, NOT A PERSONAL FAILURE.

NOT A PERSONAL FAILURE. >> TWO-THIRDS OF AMERICANS AND >> TWO-THIRDS OF AMERICANS AND HALF OF THE WORLD POPULATION DID HALF OF THE WORLD POPULATION DID NOT WAKE UP ONE MORNING AND NOT WAKE UP ONE MORNING AND DECIDE TO HAVE OBESITY. DECIDE TO HAVE OBESITY.

>> IN HER NEW BOOK, "ENOUGH," >> IN HER NEW BOOK, "ENOUGH," YOUR OPRAH TEAMS UP WITH YOUR OPRAH TEAMS UP WITH RENOWNED PHYSICIAN SCIENTIST RENOWNED PHYSICIAN SCIENTIST ANIA JASTREBOFF TO CHALLENGE ANIA JASTREBOFF TO CHALLENGE LONG-HELD BELIEFS ABOUT WEIGHT LONG-HELD BELIEFS ABOUT WEIGHT AND PEEL BACK K THE SHAME THAT AND PEEL BACK THE SHAME THAT SURROUNDED IT AND HER FOR TOO SURROUNDED IT AND HER FOR TOO LONG. LONG. JUST WEEKS SHYHY OF HER 72nd JUST WEEKS SHY OF HER 72nd BIRTHDAY, OPRAH SAYS THIS HAS BIRTHDAY, OPRAH SAYS THIS S HAS SET HER FREE.

SET HER FREE. SHE SAYS FREEDOM DIDN'T COME SHE SAYS FREEDOM DIDN'T COME FROM JUST CHANGE. FROM JUST CHANGE.

IT CAME FROM UNDERSTANDING THE IT CAME FROM UNDERSTANDING THE WHOLE PICTURE. WHOLE PICTURE. E.

AS SHE WRITES, NO AMOUNT OF AS SHE WRITES, NO AMOUNT OF SUCCESS, MONEY, FAME, OR SUCCESS, MONEY, FAME, OR INTELLIGENCE IS A MATCH FOR INTELLIGENCE IS A MATCH FOR BIOLOGY. BIOLOGY. Y.

NOW FOR HER VERY FIRST OLE SOLO NOW FOR HER VERY FIRST OLE SOLO LIVE BROADCAST INTERVIEW SINCE LIVE BROADCAST INTERVIEW SINCE THE RELEASE OF THE BOOK, OPRAH THE RELEASE OF THE BOOK, OPRAH IS HERE TO S SHARE THE WHOLE IS HERE E TO SHARE THE WHOLE PICTURE WITH US. PICTURE WITH US. >> THAT WAS GOOD.

>> OKAY. >> YEAH. >> YEAEAH.

[ CHEERS AND APPLAUSE ] [ CHEERS AND APPLAUSE ] >> SO FREEDOM IS IN THE TITLE OF >> SO FREEDOM IS IN THE TITLE OF THIS BOOK, AND YOU WRITE IN IT THIS BOOK, AND YOU WRITE IN IT THAT IT'S TAKEN YOU HALF YOUR THAT IT'S TAKEN YOU HALF YOUR LIFE TO REACH THIS MOMENT. LIFE TO REACH THIS MOMENT. WHAT DOES THAT LOOK LIKE TO YOU WHAT DOES THAT LOOK LIKE TO YOU DAY IN AND DAY OUT, THAT DAY IN AND DAY OUT, THAT FREEDOM?

FREEDODOM? >> IT LOOKS LIKE I AM NOT WAKING >> IT LOOKS LIKE I AM NOT WAKING UP AND THE FIRIRST THING I THINK UP AND THE FIRST THING I THINK ABOUT IS HOW MUCH DO I WEIGH. ABOUT IS HOW MUCH DO I WEIGH.

IT LOOKS LIKE I AM NOT THINKING IT LOOKS LIKE I AM NOT THINKING ABOUT WHAT DO HE EAT FOR BRECK ABOUT WHAT DO HE EAT FOR BRECK FOOS, AND IF I ATE BREAKFAST I FOOS, AND IF I ATE BREAKFAST I CAN'T EAT A LUNCH OROR SKIP A MEAL. THE NOISE IN MY HEAD THAT T I THE NOISE IN MY HEADAD THAT I THINK MOST PEOPLE WHO HAVE THINK MOST PEOPLE WHO HAVE OBESITY HAVE EXPERIENCED THAT OBESITY HAVE EXPERIENCED THAT FOOD NOISE THAT WE DIDN'T KNOW FOOD NOISE THAT WE DIDN'T KNOW EVERYBODY ELSE WAS HAVING. EVERYBODY ELSE WAS HAVING.

I CECERTAINLY DIDN'T KNOW THAT I CERTAINLY DIDN'T KNOW THAT PEOPLE WHO DON'T HAVE OBESITY PEOPLE WHO DON'T HAVE OBESITY DON'T HAVE IT. DON'T HAVE IT. SO IF YOU'RE LISTENINGNG TO ME W SO IF YOU'RE LISTENING TO ME NOW AND YOU DON'T WHAT I'M TALKING AND YOU DON'T WHAT I'M TALKING ABOUT, YOU PROBABLY DON'T HAVE.

ABOUT, YOU PROBABLY DON'T HAVE. IF YOU ARE LISTENING GOING, MY IF YOU ARE LISTENING GOING, MY GOD, THAT HAPPENED TO ME, TOO, GOD, THAT HAPPENED TO ME, TOO, YOU ARE STANDING FRONT OF THE YOU ARE STANDING FRONT OF THE REFRIGERATOR AND THINKING ABOUT REFRIGERATOR AND THINKING ABOUT WHAT Y YOU ARE EATING NEXT. WHAT YOU ARE EATING NEXT.

>> I THINK ABOUT TOMORROW AND >> I THINK ABOUT TOMORROW AND THE NEXT DAY. THE NEXT DAY. >> OR PLANNING THE MEAL FOR >> OR PLANNING THE MEAL FOR THANKSGIVING, , YOU KNOW, A WEEK THANKSGIVING, YOU KNOW, A WEEK BEFORE.

>> THINKING ABOUT -- >> AM I GOING TO E EAT TOO MUCH. >> AM I GOING TO EAT TOO MUCH. HOW DO I GET THAT OFF.

HOW DO I GET THAT OFF. CONSTANT NOISE HAS SUBSIDED. CONSTANT NOISE HAS SUBSIDED.

SO THAT IS WHAT HAS BEEN SO THAT IS WHAT HAS BEEN TRANSFORMATIONAL FOR ME. TRANSFORMATIONAL FOR ME. E.

AND THE NEW FREEDOM IS AND THE NEW FREEDOM IS UNDERSTANDING THAT ALL THOSE UNDERSTANDING THAT ALL THOHOSE YEARS THAT I SUFFERED AND WAS ON YEARS THAT I SUFFERED AND WAS ON THE TABLBLOIDS EVERY WEEK AND ME THE TABLOIDS EVERY WEEK AND MADE FUN OF AND THE BUTT OF FUN OF AND THE BUTT OF EVERYBODY'S JOKES, AND I THOUGHT EVERYBODY'S JOKES, AND I THOUGHT IT W WAS BECAUSE OF MY LACK OF IT WAS BECAUSE OF MY LACK OF WILLPOWER. WILLPOWEWER. WHAT IS WRONG WITH ME THAT I WHAT IS WRONG WITH ME THAT I COULD BE SUCCESSSSFUL IN SO MANY COULD BE SUCCESSFUL IN SO MANY WAYS AND I CAN'T CONQUER THIS WAYS AND I CAN'T CONQUER THIS THING.

THINING. NOW I KNOW IT HAS NOTHING TO DO NOW I I KNOW IT HAS NOTHING TO WITH WILL POWER. WITH WILL POWEWER.

IT HAS EVERYTHING TO DO WITH IT HAS EVERYTHING TO DO WITH YOUR BIOLOGY. YOUR BIOLOGY. .

>> ON THAT NOTE, I WAS THINKING >> ON THAT NOTE,E, I WAS THINKI ABOUT THIS LAST NIGHT, IN THE ABOUT THIS LAST NIGHT, IN THE SAME WAY T THAT NOW WE TALK ABOT SAME WAY THAT NOW WE TALK ABOUT MENTAL HEALTH. IT FEELS LIKE WE ARE EVOLVING. I REMEMBER, IF YOU HADAD ANXIET, I REMEMBER, IF YOU HAD ANXIETY, DEPRESSION, SHAKE IT OFF, PRAY DEPRESSION, SHAKE IT OFF, PRAY ABOUT IT, BEBE STRONG.

ABOUT IT, BE S STRONG. NOW WE REALIZE MY KIDS, YEAH, NOW WE REALIZE MY KIDS, YEAH, THERAPY IS NO BIG DEAL. THERAPY IS NO BIG DEAL.

. EVERYBODY IS A THERAPIST. EVERYBODY IS A THERAPIST.

IS THE HOPE WE CAN DO THAT -- IS THE HOPE WE CAN DO THAT -- >> WE WILL GET THERE. >> WE WILL GET THERE. .

>> WITH FOOD? >> WITH FOODOD? >> WE ARE NOT THERE YET.

>>>> WE ARE NOT THERE YET. AND THIS BOOK IS A PART OF THE AND THIS BOOK IS A PART OF THE PIONEERING OF THAT AND ALLOWING PIONEERING OF THAT AND ALLOWING PEOPLE TO LITERALLY GET THE PEOPLE TO LITERALLY GET THE MESSAGE. MESSAGE.

I KNOW IN THE BEGIGINNING WHEN E I KNOW IN THE BEGINNING WHEN THE MESSAGE, YOU ARE TRYINING TO OFR MESSAGE, YOU ARE TRYING TO OFFER THE MESSAGE, PEOPLE E LIKE, NO, THE MESSAGE, PEOPLE LIKE, NO, NO, NO, BECAUSE I REMEMBER BACK NO, NO, BECAUSE I REMEMBER BACK IN THE DAY WHEN I FIRST STARTED IN THE DAY WHEN I FIRST STARTED THE OPRAH SHOW, IN '86, '87, WE THE OPRAH SHOW, IN '86, '87, WE DID OUR FIRST SHOW ON DID OUR FIRST SHOW ON ALCOHOLISM. ALCOHOLISMSM. PEOPLE IN THE AUDIENCE LIKE, PUT PEOPLE IN THE AUDIENCE LIKE, PUT THE BOTTLE DOWN.

THE BOTTLE DOWN. PEOPLE DID NOT RECOGNIZE, PEOPLE DID NOT RECOGNIZE, REFUSED TO RECOGNIZE THAT REFUSED TO RECOGNIZE THAT ALCOHOLISM IS A DISEASE. ALCOHOLISM IS A DISEASE.

AND SO NOW WE ARE SAYING THE AND SO NOW WE ARE SAYING THE SAME THING ABOUT OBESITY. SAME THING ABOUT OBESITY. IT'S A DISEASE, IT'S A CHRONIC IT'S A DISEASE, IT'S A CHRONIC DISEASE.

DISEASE. E. YOU HAVE TO MANAGE IT.

YOU HAVE TO MANAGE IT. AND EVEN WHEN YOU THINK YOU HAVE AND EVEN WHEN YOU THINK YOU HAVE GOTTEN TO YOUR GOAL WEIGHT, IT'S GOTTEN TO YOUR GOAL WEIGHT, ITIS NOT THE ANSWER. NOT THE ANSWER.

BECAUSE YOU ARE -- WHAT THE BECAUSE YOU ARE -- WHAT THE E MEDICATIONS DO IS MANAGE THE SET MEDICATIONS DO IS MANAGE THE SET POINT IN YOUR BODY. POINT IN YOUR BODY. AND SO I WAS OFF THE MEDICATIONS AND SO I WAS OFF THE MEDICATIONS ALL LAST YEAR AND I GAINED 20 ALL LAST YEAR AND I GAINED 20 POUNDS BECAUSE I WANTED TO TEST POUNDS BECAUSE I WANTED TO TEST IT BECAUSE EVERYBODY WAS SAYING IT BECAUSE EVERYBODY WAS SAYINI YOU ARE GOING TO GAIN THE WEIGHT.

I AM GOING TO SHSHOW THEM I WON, I AM GOING TO SHOW THEM I WON'T, I WILL HIKE. I WILL HIKE. >> SO I WERE TAKING IT?

>> SO I WERE TAKING IT? >> THEN I GOT OFF OF IT. >> THEN I GOT OFF OF IT.

THEN I GAINED THREE POUNDS, THEN THEN I GAINED THREE POUNDS, THEN FIVE POUNDS, THEN TEN POUNDS. FIVE POUNDS, THEN TEN POUNDS. BEFORE YOU KNOW IT -- BEFORE YOU KNOW IT -- >> ALSO, YOU WRITE ABOUT THIS, >> ALSO, YOU WRITE ABOUT THIS, BUT GAIN THE POUNDS.

BUT GAIN THE POUNDS. MORE THAN THTHAT, THE NOISE WAS MORE THAN THAT, THE NOISE WAS BACK. BACK.

. >> THE NOISE WAS BACK. >> THE NOISE WAS BACK.

THE NOISE OF YOU ARE STANDING THE NOISE OF YOU ARE STANDING THERE LOOKING THE REFRIGERATOR, THERE LOOKING THE REFRIGERATOR, WHAT CAN I EAT? WHAT CAN I EAT? I WAS TRYING TO EAT MORE I WAS TRYING TO EAT MORE HEALTHILY AND PUT THE WEIGHT HEALTHILY AND PUT THE WEIGHT BACK ON STILL.

BACK ON STILL. THAT'S THE THING. THAT'S THE THINGNG.

IT'S THE SAME AS IF YOU ARE IT'S THE SAME AS IF YOU ARE E ON -- YOU WILL TALK TO DOCTOR ON -- YOU WILL TALK TO DOCTOR ANYA L LATER, IF YOU ARE ON BLOD ANYA LATER, IF YOU ARE ON BLOOD PRESSURE MEDICATION, IF YOU STOP PRESSURE MEDICATION, IF YOU STOP YOUR BLOOD PRESSURE MEDICATION YOUR BLOOD PRESSURE MEDICATION YOUR BLOOD PRESSURE IS GOING TO GO UP. THE SAME THING IS TRUE WITH THIS THE SAME THING IS TRUE WITH THIS MEDICATION. MEDICATIONON.

>> I FEEL LIKE MANY OF US, ALL >> I FEEL LIKE MANY Y OF US, AL OF US, AND I DON'T THINK YOU OF US, AND I D DON'T THINK YOU NECESSARILY HAVE TO HAVE OBESITY NECESSARILY HAVE TO HAVE OBESITY TO HAVE THIS, HAVE SHAME TO HAVE THIS, HAVE SHAME MOMENTS. MOMENTS. S.

SOMEBODY SAYS SOMETHING TO AND SOMEBODY SAYS SOSOMETHING TO AN IT STICKS. IT STICKS. THEN WHEN N YOU ARE TALKING BADY THENEN WHEN YOU ARE TALKING BAD TO YOURSELF LATER, YOU ARE SAYING THOSE WORDS.

YOU HAD A MOMENT WITH YOUR DADA. YOU HAD A MOMENT WITH YOUR DAD. >> YEAH.

>> YEAH. YOU KNOW WHAT? YOU KNOW WHAT?

I I DIDN'T REALIZE UNTIL MANY I DIDN'T REALIZE U UNTIL MANY YEARS LATER THAT WAS THE MOMENT YEARS LATER THAT WAS THE MOMENT FOR ME. FOR ME. I WAS IN THE HALALLWAY.

I WAS IN THE HALLWAY. I HAD GOTTEN ON A SCALE. I HAD GOTTEN ON A SCALE.

MY DAD CAME BY AS I WAS STANDING MY DAD CAME BY AS I WAS STANDING ON THE SCALE AND SAID, THERE IS ON THE SCALE AND SAID, THERE IS NO NEED TO WEIGH YOURSELF NO NEED TO WEIGH YOURSELF BECAUSE YOU ALWAYS WILL BE BIG. BECAUSE YOU ALWAYS WILL BE BIG. I WAS LIKE, WHAT?

I WAS LIKE, WHAT? YOUR MAMA IS BIG, AUNTS ARE BIG. YOUR MAMA IS BIG, AUNTS ARE BIG.

I HAD THEM IN THE BACK OF MY I HAD THEM IN THE BACK OF MY BUYOU I CAN. BUYOU I CAN. I I COULDN'T PUT THEM ALL, YOU I COULDN'T PUT THEM ALL, YOU KNOW, WEIGHING DOWN THE BACK O F KNOW, WEIGHING DOWN THE BACK OF MY BUICK.

MY BUICK. AND I WAS EMBARRASSED IN THAT AND I WAS EMBARRASSED IN THAT MOMENT, BUT I DIDN'T REALIZE MOMENT, BUT I DIDN'T REALIZE UNTIL MANY YEARS LATER BECAUSE UNTIL MANY YEARS LATER BECAUSE IT STUCK. IT STUCKCK.

AND EVERY TIME I GO ON ANOTHER AND EVERY TIME I GO ON ANOTHER DIET, I HEAR T THAT, YOU ARE DIET, I HEAR THAT, YOU ARE ALWAYS GOING TO BE BIG. ALWAYS GOING TO BE BIG. YOU'RE ALWAYS GOING TO BE BIG.

YOU'RE ALWAYS GOING TO BE BIG. YOU'RE ALWAYS GOING TO BE BIG. YOU'RE ALWAYS GOING TO BE BIG.

ALSO, LIKE I DID LAST YEAR ALSO, LIKE I DID LAST YEAR TRYING TO PROVE THE SCIENTISTS WRONG -- >> DO YOU STILL HEAR IT? >> DO YOU STILL HEARAR IT? >> NO BECAUSE I KNOW THAT, FIRST OF ALL, HE WAS WRITE RIGHT.

I WOULD ALWAYS BE BIG BECAUSE I I WOULD ALWAYS BE BIG BECAUSE I HAD THE BIOLOGOGY TO MAKE HAD THE BIOLOGY TO MAKE MYSELF -- THAT WOULD ALLOW MYSELF -- THAT WOULD ALLOW MYSELF TO BECOME OBESE. MYSELF TO BECOME OBESE. AND SO WITH THE MEDICATIONS, I AND SO WITH THE MEDICATIONS, I AM ABLE TO -- AM ABLE TO --- >> WE WILL TALK ABOUT THAT NEXT.

>> WE WILL TALK ABOUT THAT NEXT. I WILL SAY THERE ARE SO MANY MEN I WILL SAY THERE ARE SO MANY MEN AND WOMEN WHO RELATE TO WHAT YOU AND WOMEN WHO RELATE TO WHAT YOU ARE SAYING. ARE SAYING.

LAST NIGHT WHEN I READ THE BOOK, LAST NIGHT WHEN I READ THE BOOK, WHEN YOU OPEN THE BOOK, PEOPLE WHEN YOU OPEN THE BOOK, PEOPLE WILL FIND THIS, I HIGHLIGHTED WILL FIND THIS, I HIGHLIGHTETED IT, YOU SAY MAY YOU FIND PEACE Y WITH THE KNOWLEDGE THAT OBESITY IS N NOT YOUR FAULT. IS NOT YOUR FAULT. >> IT'S NOT YOUR FAULT.

>> IT'S NOT YOUR FAULT. >> ABSOLUTELY. >> THAT'S THE FREEDOM I FEEL.

AND IT'S NO LONGER MY FAULT. AND IT'S NO LONGER MY FAULT. >> NOT YOUR FAULT.

>> NOT YOUR FAULT. MUCH MORE WITH OPRAH COMING UP. MUCH MORE WITH OPRAH COMING UP.

HER CO-AUTHOR, DR. ANIA HER CO-AUTHOR, DR. ANIA JASTREBOFF JOINS US FOR THE JASTREBOFF JOINS US FOR THE CONVERSATION WITH A DEEPER DIVE CONVERSATION WITH A DEEPER DIVE INTO WEIGHT LOSS MEDICATIONS, ♪ ♪ >>> MILLIONS OF PEOPLE IN THIS >>> MILLIONS OF PEOPLE IN THIS COUNTRY STRUGGLE WITH OBESITY.

COUNTRY STRUGGLE WITH OBESITY. NOW WEIGHT LOSS MEDICATIONS ARE NOW WEIGHT LOSS MEDICATIONS ARE PROVIDING OPTION OS FOR THOSE PROVIDING OPTION OS FOR THOSE WHO STRUGGLED TO LOSE WEIGHT WHO STRUGGLED TO LOSE WEIGHT THEIR ENTIRE LIVES. THEIR ENTIRE LIVES.

>> WHAT ARE THESE GLGLP-1 MEDS D >> WHAT ARE THESE GLP-1 MEDS AND HOW DO THEY WORK. HOW DO THEY WORK. BACK TO DISCUSS, WE HAHAVE OPRAH BACK TO DISCUSS, WE HAVE OPRAH WINFREY AND JOINING THE WINFREY AND JOINING THE CONVERSATION IS ENDOCRINOLOGIST CONVERSATION IS ENDOCRINOLOGIST AND ASSOCIATE PROFESSOR AT THE AND ASSOCIATE PROFESSOR AT THE YALE SCHOOL OF MEDICINE DR.

ANIA YALE SCHOOL OF MEDICINE DR. ANIA JASTREBOFF. JASTREBOFFFF.

THEY TEAMED UP TO WRITE THIS THEY TEAMED UP TO WRITE THIS BOOK. BOOK. IT'S CALLED "ENOUGH: YOUR HEALTH, YOUR WEIGHT, AND WHAT IT'S LIKE TO BE FREE.

" IT'S LIKE TO BE FREE. " >> THE PERFECT, PERFECT TITLE. >> THE PERFECT, PERFECT TITLE.

OKAY. OKAYAY. SO OPRAH, START WITH YOU AGAIN.

SO OPRAH, START WITH YOU AGAGAI. WHEN YOU THINK BACK ABOUT ALL OF WHEN YOU THINK BACK ABOUT ALL OF THE TIME SPENT JOURNALING, THE TIME SPENT JOURNALING, SELF-HATRED, TALKING TO SELF-HATRED, TALKING TO YOYOURSELF, BLAMING YOURSELF, YU YOURSELF, BLAMING YOURSELF, YOU KNOWOW, ALL THE SHAME, ALL OF TT KNOW, ALL THE SHAME, ALL OF THAT TIME, FOR PEOPLE AT HOME WHO ARE TIME, FOR PEOPLE AT HOME WHO ARE THINKING, WAIT, THAT'S ME, LIKE, THINKING, WAIT, THAT'S ME, LIKE, WHAT DO YOU THINK ABOUT THAT WHAT DO YOU THINK ABOUT THAT TIME? TIMEME?

>> I WOULD LIKE SAY TO THE >> I WOULD LIKIKE SAY TO THE PEOPLE AT HOME, THAT'S THE PEOPLE AT HOME, THAT'S THE REASON I AM OUT IN THE STREETS. REASON I AM OUT IN THEHE STREET >> RIGHT. >> RIGHT.

>>>> OKAY? >> OKAY? THE REASON I AM OUT HERE IN THE REASON I AM OUT HERE IN THESE "TODAY" STREETS, SHEINELLE THESE "TODAY" STREETS, SHEINELLE AND JENNA, IS BECAUSE I WANT YOU AND JENNA, IS BECAUSE I WANT YOU ALL TO NOT CONTINUE TO WASTE THE ALL TO NOT CONTINUE TO WASTE THE TIME.

TIME. I WANT P PEOPLE TO UNDERSTAND, I WANT PEOPLE TO UNDERSTAND, IT'S NOT YOUR FAULT. IT'S NOT YOUR FAULT.

>> YES. H >> YOU CANNOT SOLVE THIS WITH WILL POWER BECAUSE THE TRUTH IS, WILL POWER BECAUSE THE TRUTH IS, IF YOU COULD HAVE SOLVED IT WITH IF YOU COULD HAVE SOLVED IT WITH WILL POWER, WE WOULD HAVE DONE WILL POWER, WE WOULD HAVE DONE IT. >> THAT'S WHAT HE WANTS.

>> WHAT DO Y YOU MEAN BY ENOUGH? >> WHAT DO YOU MEAEAN BY ENOUGH? >> YEAH, SO ENOUGH REALLY COMES >> YEAH, SO ENOUGH REALLY COMES TO THE ENOUGH POINT.

TO THE ENOUGH POINT. >> YES. >> YES.

>> WHICH O OPRAH HAS TALKED ABOT >> WHICH OPRAH HAS TALKED ABOUT AND HAS TALKED ABOUT RECENTLY IN AND HAS TALKED ABOUT RECENTLY IN TERMS OF THAT IS WHERE HER BODY TERMS OF THAT IS WHERE HER BODY ALWAYS WANTED TO BE. ALWAYS WANTED TO BE. AND D THE ENOUGH POINT IS HOW MH AND THE ENOUGH POINT IS HOW MUCH ENERGY, HOW MUCH FUEL, HOW MUCH ENERGY, HOW MUCH FUEL, HOW MUCH FAT YOUR BODY WANTS YOU TO FAT YOUR BODY WANTS YOU TO STORE.

STORE. E. AND IT FIGHTS NO MATTER WHAT TO AND IT FIGHTS NO MATTER WHAT TO TRY TO GET YOU TO THAT -- TRY TO GET YOU TO THAT -- >> WHAT IF YOUR ENOUGH POINT IS >> WHAT IF YOUR ENOUGH POINT I BIGGER WHERE THAN YOU WANT IT TO BIGGER WHERE THAN YOU WANT IT TO BE?

HOW DO YOU -- >> AS I SASAID, MY ENOUGH POINT, >> AS I SAID, MY ENOUGH POINT, EVERY TIME I WENT ON A DIET, EVERY TIME I WENT ON A DIET, BETWEEN 211 AND 218. BETWEEN 211 AND 218. WHEN I PULLED OUT THE WAGON OF WHEN I PULLED OUT THE WAGON OF FAT SO MANY YEARS AGO, I WAS FAT SO MANY YEARS AGO, I WAS 211.

211. 1. RUN THE MARATHON, SAME THING.

RUN THE MARATHON, SAME THING. MY ENOUGH POINT IS FAR HIGHEHER MY ENOUGH POINT IS FAR HIGHER THAN WITH I REALLY WANTED TO BE. THAN WITH I REALLY WANTED TO BE.

I THINK FOR A LOT OF PEOPLE WHO I THINK FOR A LOT OF PEOPLE WHO DON'T HAVE OBESITY, THEIR ENOUGH DON'T HAVE OBESITY, THEIR ENOUGH OR SET POINT IS MUCH LOWER. OR SET POINT IS MUCH LOWER. .

>> IT'S MUCH LOWER. >> IT'S MUCH LOWER. AND THE E IDEA FOR THE BOOK, THE AND THE IDEA FOR THE BOOK, THE TITLE "ENOUGH," CAME TO ME ONE TITLE "ENOUGH," CAME TO ME ONE MORNING.

MORNING. G. I WOKE UP AND RAN DOWN THE I WOKE UP AND RAN DOWN THE STAIRS AND LITERALLY WROTE IT STAIRS AND LITERALLY WROTE IT DOWN ON A POST-IT NOTE.

DOWN ON A POST-IT NOTE. I WAS SO EXCITED. I WAS SO EXCITED.

THE REASON IS BECAUSE ITIT REALY THE REASON IS BECAUSE IT REALLY CAPTURES WHAT HAPPENS WHEN CAPTURES WHAT HAPPENS WHEN PEOPLE, WHEN OPRAH TAKES THE PEOPLE, WHEN OPRAH TAKES THE MEDICINE, SHE FEELS SHE HAS MEDICINE, SHE FEELS SHE HAS S ENOUGH. ENOUGH. PEOPLE WHO HAVE OBESITY, THEIR PEOPLE WHO HAVE OBESITY, THEIR BRAIN, WHICH SETS THE ENOUGH BRAIN, WHICH SETS THE ENOUGHGH POINT, IS CONSTANTLY PULLING TH POINT, IS CONSTANTLY PULLING TH AND THEY HE WILL DON'T F FEEL LE AND THEY HE WILL DON'T FEEL LIKE THEY HAVE ENOUGH.

THEY HAVE ENOUGH. THE TITLE MEANS SOMETHING ELSE. THE TITLE MEANS SOMETHING ELSE.

ENOUGH BLAME AND SHAME. WHY ARE WE BLAMING PEOPLE FOR A DOZEN THAT IS NOT THEIR FAULT, DOZEN THAT IS NOT THEIR FAULT, NOT THEIR CHOICE. NOT THTHEIR CHOICE.

AND SO THAT'S WHY THE TITLE FIT AND SO THAT'S WHY THE TITLE FIT SO PERFECTLY. SO PERFECTLY. >> IF ANYBODY IS WATCHING NOW AND HAS OBESITY, YOU KNOW HOW YOU CONTINUE TO EAT EVEN THOUGH YOU CONTINUE TO EAT EVEN THOUGH YOU ARE FULL OR YOU HAD ENOUGH YOU ARE FULL OR YOU HAD ENOUGH BUT IT'S STILL ON THE PLATE, SO BUT IT'S STILL ON THE PLATE, SO YOU CONTINUE TO EAT BECAUSE YOU YOU CONTINUE TO EAT BECAUSE YOU GREW UP IN THE CLEAN PLATE CLUB.

GREW UP IN THE CLEAN PLATE CLUB. >> DO YOU NOT DO THAT? >> DO YOU NOT DO THAT?

>> THAT STOPS WITH THE >> THAT STOPS WITH THE MEDICATION. >> LET'S TALK -- >> TWO ENGLISH MUFFINS E EVERY >> TWO ENGLISH MUFFINS EVERY MORNING, ONE WITH HONEY, ONE MORNING, ONE WITH HONEY, ONE WITH JAM, ONE WITH EGG. WITH JAM, ONE WITH EGG.

NOW I CAN DO ONE OR A HALF OF NOW I CAN DO ONE OR A HALF OF ONE. ONE. E.

>> YOU ARE NOT HUNGRY? >> YOU ARE NOT HUNGRY? >> YOU HAVE ENOUOUGH.

>> YOU HAVE ENOUGH. >> LET'S TALK ABOUT THAT. >> LET'S TALK ABOUT THAT.

. LET'S TALK ABOUT THE GLP-1s OR LET'S TALK ABOUT THE GLP-1s OR THE OBESITY MEDICINE AS YOU CALL THE OBESITY MEDICINE AS YOU CALL THEM. THEMEM.

AND WHAT HAPPENS WHEN YOU GO AND WHAT HAPPENS WHEN YOU GO OFF? OFF? F?

I MEAN, AND I LOVE THAT YOU I MEAN, AND I LOVE THAT YOU TESTED IT. TESTED IT. >> I WAS GOING TO PROVE E HER >> I WAS GOING TO PROVE HER WRONG BECAUSE I WAS SASAYING, N, WRONG BECAUSE I WAS SAYING, NO, I'M HIKING AND SEVEN MILES AND I'M HIKING AND SEVEN MILES AND DOING THIS.

DOING THIS. I DON'T KNOW. I DON'T KNOW.

I THINK YOU ARE GOING TO HAVE AN I THINK YOU ARE GOING TO HAVE AN ISSUE. ISSUE. E.

NO, NO, NO, NO. NO, NO, NO, NO. AND THEN IT SUDDENLY CAME BACK.

AND THEN IT SUDDENLY CAME BACK. >> IT'S BIOLOGY, RIGHT? >> IT'S BIOLOGY, RIGHT?

>> IT'S ABOUT BIOLOGY. >> IT'S ABOUT BIOLOGY. I DON'T KNOW ANYONE THAT HAS I DON'T KNOW ANYONE THAT HAS MORE GRITMAN OPRAH.

MORE GRITMAN OPRAH. SHE IS HIKING E SIX, SEVEN, EIGH SHE IS HIKING E SIX, SEVEN, EIGH MILES A DAY, EATING RIGHT. MILES A DAY, EATING RIGHT.

THREE KEPT ON BEING PULLED UP. THREE KEPT ON BEING PULLED U UP. THE MEDICINES, WHAT THEY DO, THE THE MEDIDICINES, WHAT THEY DO, E WAY THEY WORK, THEY RECALIBRATE, WAY THEY WORK, THEY RECACALIBRA, THEY LOWER YOUR ENOUGH POINT SO THEY LOWER YOUR ENOUGH POINT SO THAT YOUR BRAIN IS LIKE, HEY THAT YOUR BRAIN IS LIKE, HEY BODY, YOU ARE NOT STARVING, YOU BODY, YOU ARE NOT STARVING, YOU DO NOT NEED TO EAT MORE, YOU DO NOT NEED TO EAT MORE, YOU HAVE ENOUGUGH FUEL, YOU HAVE HAVE ENOUGH FUEL, YOU HAVE ENOUGH FAT, YOU HAVE ENOUGH.

ENOUGH FAT, YOU HAVE ENOUGH. AND THAT IS WHY ONE MUFFIN OR AND THAT IS WHY ONE MUFFIN OR HALF A MUFFIN IS ENOUGH. HALF A MUFFIN IS ENOUGH.

>> ARE THERE SIDE EFFECTS? >> ARE THERE SIDE EFFECTS? >> I AM SURE PEOPLE ARE >> I AM SURE PEOPLE ARE WATCHING, IT'S PROBABLY NOT FOR WATCHING, IT'S PROBABLY NOT FOR EVERYBODY.

EVERYBODY. WHAT DO WE NEED TO KNONOW AND FR WHAT DO WE NEED TO KNOW AND FOR SIDE EFFECTS? SIDE EFFECTS?

>> EVERY MEDICICINE FOR ANY >> EVERY MEDICINE FOR ANY DISEASE HAS SIDE EFFECTS. DISEASE HAS SIDE EFFECTSTS. THAT'S THE FIRST THING.

IO THERE IS A RISK TO BENEFIT RATIO FOR EVERY PERSON. FOR EVERY PERSON. THEY ARE NOT RIGHT FOR THEY ARE NOT RIGHT FOR EVERYBODY.

WHAT ARE THE COMMON SIDE EFFECTS, THERE A ARE MANY WAYS O EFFECTS, THERE ARE MANY WAYS TO MITIGATE THEM, LOWOWER THE CHANE MITIGATE THEM, LOWER THE CHANCE OF T THEM. OF THEM. THE MOST COMMON SIDE EFFFFECTS E THE MOST COMMON SIDE EFFECTS ARE NAUSEA, DIARRHEA, CONSTIPATION.

NAUSEA, DIARRHEA, CONSTIPATION. THE BEST WAY -- THE BEST WAY --- >> HAVE YOU EVER HAD NAUSEA OR DIARRHEA, BUT I DID HAVE THE THIRD ONE. THIRD ONE.

>> SO IMPORTANT -- >> SO IMPORTANT T -- >> THERE ARE WAYS TO MITIGATE THAT? >> I FIGURED OUT FOR ME WHAT THE >> I FIGURED OUT FOR ME WHAT THE RIGHT COMBINATION OF MAGNESIUM RIGHT COMBINATION OF MAGNESIUM AND WATER IS. AND WATER IS.

>> DRINK A A LOT OF WATER. >> DRINK A LOT OF WATER. >> I AM ALWAYS URIAS.

>> I AM ALWAYS URIAS. >> I HAVE TO HAVE A GALLON OF >> I HAVE TO HAVE A GALLON OF WATER A DAY. WATER A DAY.

Y. A GALLON OF WATER A DAY. A GALLON OF WATER A DAY.

>> I LOVE THAT WE HAVE OUR NEW >> I LOVE THAT WE HAVE OUR NEW MUGS. MUGS. >> WOULD YOU LIKE A MUG?

>> WOULD YOU LIKE A MUG? >> SOME OF YOUR WATER? >> SOME OF YOUR WATER?

>> A GALLON OF WATER. >> A GALLON OF WATER. IF I DO LESS AND I HAVE TO DRINK A GALLON OF WATER BEFORE 4:00.

>> STOP IT. >> STOP IT. >> A GALLON OF WATER?

>> A GALLON OF WATER? >> IT'S GOING TO BE ROUGH >> IT'S GOING TO BE ROUGH BECAUSE IT'S HARD -- BECAUSE IT'S HARD -- >> OPRAH'S KIDNEYSYS ARE VERY, >> OPRAH'S KIDNEYS ARE VERY, VERY HAPPY. VERY HAPPYPY.

HYDRATION IS ONE OF THE BEST HYDRATION IS ONE OF THE BEST WAYS T TO MITIGATE NAUSEA OR TO WAYS TO MITIGATE NAUSEA OR TO LESSEN NAUSEA. LESSEN NAUSEA. THERE ARE OTHER WAYS.

THERE ARE OTHER WAYS. THE MOSTST IMPORTANT WAY IS THE MOST IMPORTANT WAY IS WORKING WITH YOUR HEALTH CARE WORKING WITH YOUR HEALTH CARE PRPROVIDER AND GOING UP VERY, VY PROVIDER AND GOING UP VERY, VERY SLOWLY. SLOWLY.

. START LOW. START T LOW.

GO SLOW. GO SLOW. IF YOU ARE FEELING NAUSEATED, IF YOU ARE FEELING NAUSEATED, DON'T INCREASE THE DOSE.

DON'T INCREASE THE DOSE. THERE IS OTHER THINGS. THERE IS OTHER THINGNGS.

NOT EATING PAST THE POINT OF NOT EATING PAST THE POINT OF FULLNESS, MAKE SURE YOU MONITOR FULLNESS, MAKE SURE YOU MONITOR WHICH FOODS MAYBE YOU WORSE. WHICH FOODS MAYBE YOU WORSE. DIFFERENT THINGS CAN LOWER THE DIFFERENT THINGS CAN LOWER THE SIDE EFFECTS.

SIDE EFFECTS. >> FOR EVERYBODY WHO WANTS TO >> FOR EVEVERYBODY WHO WANTS TO ASK THE QUESTION, DO YOU STAY ON ASK THE E QUESTION, DO YOU STAYN IT, IF YOU ARE ON BLOOD PRESSURE IT, IF YOU ARE ON BLOOD PRESSURE MEDICATION, IF YOU'RE ON MEDICATION, IF YOU'RE ON DIDIABETES MEDICATION OR ANY OTR DIABETES MEDICATION OR ANY OTHER MEDICACATION FOR A CHRONIC MEDICATION FOR A CHRONIC DISEASE, T THIS IS A CHRONIC DISEASE, THIS IS A CHRONIC DISEASE. DISEASE.

IF Y YOU ARE BLOOD PRESSURE IF YOU ARE BLOOD PRESSURE MEDICATION YOU GET YOUR BLOOD PRESSURE TO THE LEVEL YOUR DOCTOR SAYS IS HEALTHY FOR YOU, DOCTOR SAYS IS HEALTHY FOR YOU, COCOME OFF THE MEDICATION, YOUR COME OFF THE MEDICATION, YOUR BLOOD PRESSURE GOES UP. BLOOD PRESSURE GOES UPUP. THE SAME THING IS TRUE FOR THIS.

THE SAME THING IS TRUE FOR THIS. I KNOW IT BECAUSE I PROVED IT. I KNOW IT BECAUSE I PROVED IT.

>> REWIRE HOW WE THINK ABOUT IT. >> REWIRE HOW WE THINK ABOUT IT. >> YES, YES.

>> YES, YES. AND I LOOK AT IT AS A TOOL. AND I LOOK AT IT AS A TOOL.

A TOOL TO HELP ME MANAGE MY A TOOL TO HELP ME MANAGE MY ENTIRE HEALTH. ENTIRE HEALTH. >> AND BY THE WAY, YOUR HEALTH, >> AND BY THE WAY, YOUR HEALTH, YOU HIKE SOMETHING LIKE EIGHT YOU HIKE SOMETHING LIKE EIGHT MILES -- MILES S -- >> NO, I DID TEN MILES OVER THE >> NO, I DID TEN MILES OVER THE HOLIDAYS FOR -- HOLIDAYS FOR -- >> LOOK.

>> LOOK. >> YES, YES. >> YES, YEYES.

>> YOU HIKE LIKE CRAZY. >> YOU HIKE LILIKE CRAZY. YOU ARE LIFTING, WHICH IS YOU ARE LIFTING, WHICH IS IMPORTANT FOR WOMEN.

IMPORTANT FOR WOMEN. >> RESISTANCE TRAINING IS REALLY >> RESISTANCE TRAINING IS REALLY IMPORTANT AS YOU GET OLDER FOR IMPORTANT AS YOU GET OLDER FOR MUSCLE TONE. MUSCLE TONONE.

>> SO MANY PEOPLE YOU TALK ABOUT >> SO MANY PEOPLE YOU TALK ABOUT HIKING AND YOU DO SOMETHING, HIKING AND YOU DO SOMETHING, PEOPLE ARE HERE FOR IT, RIGHT, PEOPLE ARE HERE FOR IT, RIGHT, AND A LOT OF PEOPLE, I CAN'T AND A LOT OF PEOPLE, I CAN'T WALK, , I CAN'T DO THIS. WALK, I CAN'T DO THIS. WHAT IS IT ABOUT HIKING THAT YOU WHAT IS IT ABOUT HIKING THAT YOU LOVE THAT MAYBE SOMEONE AT HOME LOVE THAT MAYBE SOMEONE AT HOME WATCHING CAN SAY, YOU KNOW WHAT?

WATCHING CAN SAY, YOU KNOW WHAT? LET ME GIVE IT A TRY. LET ME GIVE IT A TRY.

>> THE REASON I LOVE HIKING -- I >> THE REASON I LOVE HIKING -- I LOVE THAT QUESTION. LOVE THAT QUESTION. THE REASON I LOVE HIHIKING SO THE REASON I LOVE HIKING SO MUCH, YOU ARE LOOKING AT THE TOP MUCH, YOU ARE LOOKING AT THE T P OF THE HILL AND THIS IS WHAT OF THE HILL L AND THIS IS WHAT HAPPENED WHEN I GOT MY KNEES HAPPENED WHEN I GOT MY KNEES DONE.

DONE. . I LOOK OUT THE WINDOW BECAUSE I I LOOK OUT THE WINDOW BECAUSE I COULDN'T WALK.

COULDN'T WALK. I WOULD LIKE T TO GET TO THE TOP I WOULD LIKE TO GET TO THE TOPO OF THAT HILL. OF THAHAT HILL.

YOU LOOK AT THE TOP OF THE HILL. . THIS IS WHAT I LOVE ABOUT IT.

DON'T LOOK HOW FAR YOU HAVE GO. DON'T LOOK HOW FAR YOU HAVE GO. EVERY STEP YOU TAKE, TURN AROUND EVERY STEP YOU TAKE, TURN AROUND AND LOOK HOW FAR YOU'VE COME.

AND LOOK HOW FAR YOU'VE COME. LOOK HOW FAR YOU HAVE COME. LOOK HOW FAR YOU HAVE COME.

YOU GET HALFWAY THERE, LOOK HOHW YOU GET HALFWAY THERE, LOOK HOW FAR YOU'VE COME. FAR YOU'VE COME. THAT GIVES YOU THE F FUEL AND TE THAT GIVES YOU THE FUEL AND THE STRENGTH TO KEEP YOURSELF GOING.

STRENGTH TO KEEP YOURSELF GOING. THAT'S A GREAT METAPHOR FOR THAT'S A GREAT METAPHOR FOR LIFE. LIFE.

. DON'T LOOK HOW FAR YOU HAVE GO. DON'T LOOK HOW FAR YOU HAVE GO.

LOOK HOW FAR YOU'VE COME. LOOK HOW FAR YOU'VE COME. >> BY THE WAY -- >> BY THE WAY -- [ [ CHEERS AND APPLAUSE ] !

>> I LOVE IT! >> I QUOTED IT LAST WEEK. >> I QUOTED IT LAST WEEK.

I QUOTED IT. I QUOTED IT. IT'S BEAUTIFUL.

IT'S BEAUTIFUL. . >> THAT'S A SERMON.

>> THAT'S A SERMON. >> THANK YOU SO MUCH F FOR BEING >> THANK YOU SO MUCH FOR BEING HERE AND THIS BEAUTIFUL BOOK. HERE AND THIS BEAUTIFUL BOOK.

. >> SO HAPPY TO BE HERE ON YOUR >> SO HAPPY TO BE HERE ON YOUR SECOND DAY. SECOND DAY.

[ CHEERS A AND APPLAUSE ] [ CHCHEERS AND APPLAUSE ] >> I DON'T KNOW HOW WE ARE GOING TO GO UP FROM HERE. >> YOU WILL. >> YOU WILL.

>> WE'LL TRY. >> WE'LL TRY. >> THANK YOU AS WEWELL.

>> THANK YOUOU AS WELL.